Background: Primary palmar hyperhidrosis is a disorder resulting in abnormally excessive sweating of palmar side of hand. Patients present with cold and wet hands. It can also occur in combination with other areas like soles, axillae, and craniofacial region. Objective: To estimate prevalence of primary palmar hyperhidrosis in Faisalabad and its impact on hand grip strength and quality of life. Methods: This analytical cross-sectional study was conducted at Dermatology departments of three tertiary care hospitals of Faisalabad, Pakistan. Sample size was calculated using formula. Both genders with age ranging from 15 to 65 years were selected as participants using convenient sampling. Participants filled self made form which included demographics, screening and valid and reliable quality of life measuring tools (HDSS and Keller scale). Then, after screening, grip strengths of hyperhidrotics (group 1) and non-hyperhidrotics (group 2) were measured using modified sphygmomanometer test (cuff method) and were compared. Data were analyzed using SPSS version 22. Results: Prevalence of primary palmar hyperhidrosis was 15.5% (11/71) consisting of 6 females and 5 males. Age of onset occurred during 5-15 years. 63.64% patients had positive family history. 90.91% patients had normal (18.5-24.9) BMI. Mean right and left grip strength values of hyperhidrotic patients were 168.55±55.446 and 157.55±44.568, respectively. Mean right and left grip strength values in non-hyperhidrotic participants were 157.63±53.126 and 148.67±53.85, respectively. 54.55% patients reported 3 on HDSS. On Keller scale majority reported mild to severe distress especially when shaking hands with others, writing papers, driving cars, grasping heavy objects, and wearing gloves. Conclusion: Current study showed 15.5% prevalence rate of primary palmar hyperhidrosis. Hand grip strength values of hyperhidrotic patients were higher when compared with non-hyperhidrotic participants. Majority of patients reported barely tolerable sweating which resulted in mild to severe distress experienced during activities of daily living.
背景:原发性手掌多汗症是一种导致手掌侧异常过度出汗的疾病。患者出现双手冰冷潮湿。它也可以与其他区域如鞋底、腋窝和颅面区域合并发生。目的:评估费萨拉巴德市原发性手掌多汗症的患病率及其对握力和生活质量的影响。方法:本分析横断面研究在巴基斯坦费萨拉巴德三所三级医院的皮肤科进行。用公式计算样本量。采用方便抽样法，选取年龄在15 ~ 65岁的男女作为研究对象。参与者填写自己制作的表格，包括人口统计、筛选和有效可靠的生活质量测量工具(HDSS和Keller量表)。筛选后，采用改良血压计试验(袖带法)测量多汗症(1组)和非多汗症(2组)患者的握力，并进行比较。数据分析采用SPSS version 22。结果:原发性掌多汗症患病率为15.5%(11/71)，其中女性6例，男性5例。发病年龄为5-15岁。63.64%患者有阳性家族史。90.91%的患者BMI正常(18.5 ~ 24.9)。多汗症患者左右握力平均值分别为168.55±55.446、157.55±44.568。非多汗症患者左右握力平均值分别为157.63±53.126和148.67±53.85。54.55%的患者出现HDSS。在凯勒量表中，大多数人表示轻微到严重的痛苦，尤其是在与他人握手、写文件、开车、抓重物和戴手套时。结论:原发性手掌多汗症的患病率为15.5%。多汗症患者的握力值高于非多汗症患者。大多数患者报告几乎无法忍受出汗，导致在日常生活活动中经历轻微到严重的痛苦。
{"title":"Prevalence of Primary Palmar Hyperhidrosis and its Impact on Hand Grip Strength and Quality of Life","authors":"Duaa Ejaz Saigaal, Anam Shahzad, Ramesha Tahir, Iqra Waseem, Qurat-Ul- Ain, Komal Tariq","doi":"10.21649/akemu.v29i2.5504","DOIUrl":"https://doi.org/10.21649/akemu.v29i2.5504","url":null,"abstract":"Background: Primary palmar hyperhidrosis is a disorder resulting in abnormally excessive sweating of palmar side of hand. Patients present with cold and wet hands. It can also occur in combination with other areas like soles, axillae, and craniofacial region. Objective: To estimate prevalence of primary palmar hyperhidrosis in Faisalabad and its impact on hand grip strength and quality of life. Methods: This analytical cross-sectional study was conducted at Dermatology departments of three tertiary care hospitals of Faisalabad, Pakistan. Sample size was calculated using formula. Both genders with age ranging from 15 to 65 years were selected as participants using convenient sampling. Participants filled self made form which included demographics, screening and valid and reliable quality of life measuring tools (HDSS and Keller scale). Then, after screening, grip strengths of hyperhidrotics (group 1) and non-hyperhidrotics (group 2) were measured using modified sphygmomanometer test (cuff method) and were compared. Data were analyzed using SPSS version 22. Results: Prevalence of primary palmar hyperhidrosis was 15.5% (11/71) consisting of 6 females and 5 males. Age of onset occurred during 5-15 years. 63.64% patients had positive family history. 90.91% patients had normal (18.5-24.9) BMI. Mean right and left grip strength values of hyperhidrotic patients were 168.55±55.446 and 157.55±44.568, respectively. Mean right and left grip strength values in non-hyperhidrotic participants were 157.63±53.126 and 148.67±53.85, respectively. 54.55% patients reported 3 on HDSS. On Keller scale majority reported mild to severe distress especially when shaking hands with others, writing papers, driving cars, grasping heavy objects, and wearing gloves. Conclusion: Current study showed 15.5% prevalence rate of primary palmar hyperhidrosis. Hand grip strength values of hyperhidrotic patients were higher when compared with non-hyperhidrotic participants. Majority of patients reported barely tolerable sweating which resulted in mild to severe distress experienced during activities of daily living.","PeriodicalId":43918,"journal":{"name":"Annals of King Edward Medical University Lahore Pakistan","volume":"20 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135477364","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-27DOI: 10.21649/akemu.v29i2.5440
Akhtar Sherin
Journal Impact Factor (JIF), proposed by Eugene Garfield in early 1960s, is considered as the one of the most widely recognized and influential metrics for scholarly journal ranking in the world. It provided a standardized measure based on the citation data for evaluation of journals. In 1975, the Institute for Scientific Information introduced the initial version of the Journal Citation Reports (JCR) as an essential part of the Science Citation Index, spearheaded by Eugene Garfield. First JCR was based on 4,248,065 citations of around 400,OOO source items published during 1974 in 2400 journals.1 Since then, JCR & JIF have undergone significant developments and transformations. They became widely adopted tools for evaluating research impact and journal prestige. Over the years, the IF and JCR expanded their coverage, incorporating more journals and disciplines. Recently released JCR 2023 comprised of 21,522 journals (including 13,668 science journals) from 112 countries across 254 research disciplines.2
{"title":"THE ROAD LESS TRAVELED: NURTURING A MEDICAL JOURNAL'S QUEST FOR INTERNATIONAL INDEXATION AND IMPACT FACTOR","authors":"Akhtar Sherin","doi":"10.21649/akemu.v29i2.5440","DOIUrl":"https://doi.org/10.21649/akemu.v29i2.5440","url":null,"abstract":"Journal Impact Factor (JIF), proposed by Eugene Garfield in early 1960s, is considered as the one of the most widely recognized and influential metrics for scholarly journal ranking in the world. It provided a standardized measure based on the citation data for evaluation of journals. In 1975, the Institute for Scientific Information introduced the initial version of the Journal Citation Reports (JCR) as an essential part of the Science Citation Index, spearheaded by Eugene Garfield. First JCR was based on 4,248,065 citations of around 400,OOO source items published during 1974 in 2400 journals.1 Since then, JCR & JIF have undergone significant developments and transformations. They became widely adopted tools for evaluating research impact and journal prestige. Over the years, the IF and JCR expanded their coverage, incorporating more journals and disciplines. Recently released JCR 2023 comprised of 21,522 journals (including 13,668 science journals) from 112 countries across 254 research disciplines.2","PeriodicalId":43918,"journal":{"name":"Annals of King Edward Medical University Lahore Pakistan","volume":"48 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135475916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-27DOI: 10.21649/akemu.v29i2.5505
Lubna Maqsud Cheema, Zahid Tayyab, Sobia Manzoor, Romaisa Shamim Khan, Muhammad Mustehsan Bashir, Sehrish Ijaz
Background: Negative pressure wound therapy ( NPWT ) has been commonly used in the management of complex traumatic wounds of extremities. It reduces oedema, increases perfusion and enhances granulation tissue formation. But presence of external fixator makes it difficult to apply and maintenance of seal in presence of external fixator thus affecting wound healing. Objective: To study the effective application and outcome of NPWT in the management of complex wounds. Methods: Retrospective study conducted in Department of Plastic and Reconstructive Mayo Hospital/KEMU over a period of 2 years (June20- June 22). All patients presenting with wounds on either upper or lower limb with external fixator applied during this period were included. After wound debridement NPWT was applied
according to our technique. Demographic data of patients, mode of injury, time of presentation after injury and site/size of wound were noted. Outcome of seal (Effective maintenance of suction pressure at the completion of NPWT application and Seal failure as loss of suction within 72 hrs ) , no. of NPWT sessions and outcome of wound (skin grafting/flaps) were documented. Results: In this study, total number of patients was 26. Seventeen were (65.4%) males and 9(34.6%) females. Mode of injury was road traffic accident (69.8%) and machine injury (30.8%). Mean age was 23±14.2 years. Mean wound size 31.3±12.6 in2. Mean time of presentation after injury was 11.8±6.14 days. In 3 patients seal was not maintained. In 23 patients seal was maintained. Skin grafting was done in 21 patients and local/ distant flaps in 5 patients. Conclusion: NPWT has been in use for the management of wounds for many years. But problem arises in its application over wounds with external fixator. There are chances of air leakage and difficulty in maintaining seal. With our technique of application, we have been able to manage this problem. It is a simple, quick and inexpensive technique with overall good results. Use of this technique minimizes the use of major local and free flaps for soft tissue coverage of limbs.
{"title":"Effective Application and Outcome of Negative Pressure Wound Therapy in Management of Complex Wounds with External Fixator","authors":"Lubna Maqsud Cheema, Zahid Tayyab, Sobia Manzoor, Romaisa Shamim Khan, Muhammad Mustehsan Bashir, Sehrish Ijaz","doi":"10.21649/akemu.v29i2.5505","DOIUrl":"https://doi.org/10.21649/akemu.v29i2.5505","url":null,"abstract":"Background: Negative pressure wound therapy ( NPWT ) has been commonly used in the management of complex traumatic wounds of extremities. It reduces oedema, increases perfusion and enhances granulation tissue formation. But presence of external fixator makes it difficult to apply and maintenance of seal in presence of external fixator thus affecting wound healing. Objective: To study the effective application and outcome of NPWT in the management of complex wounds. Methods: Retrospective study conducted in Department of Plastic and Reconstructive Mayo Hospital/KEMU over a period of 2 years (June20- June 22). All patients presenting with wounds on either upper or lower limb with external fixator applied during this period were included. After wound debridement NPWT was applied
 according to our technique. Demographic data of patients, mode of injury, time of presentation after injury and site/size of wound were noted. Outcome of seal (Effective maintenance of suction pressure at the completion of NPWT application and Seal failure as loss of suction within 72 hrs ) , no. of NPWT sessions and outcome of wound (skin grafting/flaps) were documented. Results: In this study, total number of patients was 26. Seventeen were (65.4%) males and 9(34.6%) females. Mode of injury was road traffic accident (69.8%) and machine injury (30.8%). Mean age was 23±14.2 years. Mean wound size 31.3±12.6 in2. Mean time of presentation after injury was 11.8±6.14 days. In 3 patients seal was not maintained. In 23 patients seal was maintained. Skin grafting was done in 21 patients and local/ distant flaps in 5 patients. Conclusion: NPWT has been in use for the management of wounds for many years. But problem arises in its application over wounds with external fixator. There are chances of air leakage and difficulty in maintaining seal. With our technique of application, we have been able to manage this problem. It is a simple, quick and inexpensive technique with overall good results. Use of this technique minimizes the use of major local and free flaps for soft tissue coverage of limbs.","PeriodicalId":43918,"journal":{"name":"Annals of King Edward Medical University Lahore Pakistan","volume":"72 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135477363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-27DOI: 10.21649/akemu.v29i2.5507
Zahid Kamal Siddiqui, Asima Rafique, Muhammad Shaheer
Background: Globally, 80 % of the visual loss is preventable. A major proportion of patients presenting in tertiary care hospitals is that of ophthalmology constituting 20% emergency patients and 18 % outpatient consultations. Objective: To compare the effect of slit lamp teaching versus bedside teaching in ophthalmology residency at a tertiary level teaching hospital. Methodology: This questionnaire based cross sectional survey was conducted after ethical approval at College of Ophthalmology and Allied Vision Sciences/Institute of Ophthalmology, Mayo Hospital, Lahore. Ophthalmology residents from first to fourth year of their training program were included in the study while Consultants, medical officers, fellows and house officers were excluded from the study. A web based close ended questionnaire (Google form) was developed consisting of 13 questions covering different aspects of slit lamp and bedside teaching. Paired sample t-test was applied to check significance among two methods. Results: Upon stratification of the data based on year of residency training, among 3rd year residents, the mean score of bedside teaching was significantly reduced as compared to slit lamp teaching [1.29±0.48 vs 1.86±0.37, t(6) = 2.828, p = 0.03] when they were asked whether practical skills trainings facilitated. Moreover,
mean score of bedside teaching was significantly reduced as compared to slit lamp teaching among 1st year and 3rd year students when they responded to the question “Is clinical reasoning demonstrated”, 1st year: 1.13± 0.64 vs 1.75±0.46. t(7) = 3.416, p = 0.011 and for 3rd year: 1.14±0.37 vs 2.00±0.00, t(6) = 6.00, p = 0.001. Conclusion: Both slit lamp Teaching and Bedside teaching are vital in ophthalmology residency as they complement each other in making up shortcomings of each other.
背景:在全球范围内，80%的视力丧失是可以预防的。在三级保健医院就诊的病人中，主要是眼科病人，占急诊病人的20%，门诊病人的18%。目的:比较裂隙灯教学与床边教学在三级教学医院眼科住院实习中的效果。方法:本问卷式横断面调查是在拉合尔梅奥医院眼科和联合视觉科学学院/眼科研究所经伦理批准后进行的。接受培训第一至第四年的眼科住院医生被纳入研究，而顾问、医务人员、研究员和住院医生被排除在研究之外。一个基于网络的封闭式问卷(Google表单)由13个问题组成，涵盖裂隙灯和床边教学的不同方面。采用配对样本t检验检验两种方法之间的显著性。结果:根据住院医师培训年份对数据进行分层，当被问及实践技能培训是否促进时，在三年级住院医师中，床边教学的平均得分明显低于裂隙灯教学[1.29±0.48 vs 1.86±0.37,t(6) = 2.828, p = 0.03]。此外,& # x0D;在回答“临床推理是否被证明”的问题时，一年级和三年级学生床边教学的平均得分明显低于裂隙灯教学，一年级:1.13±0.64比1.75±0.46。T (7) = 3.416, p = 0.011，第三年:1.14±0.37 vs 2.00±0.00,T (6) = 6.00, p = 0.001。结论:裂隙灯教学与床边教学在眼科住院医师实习中具有重要作用，两者相辅相成，取长补短。
{"title":"Comparison of Slit Lamp Teaching Versus Bedside Teaching in Post Graduate Ophthalmology Residency at a Teaching Hospital","authors":"Zahid Kamal Siddiqui, Asima Rafique, Muhammad Shaheer","doi":"10.21649/akemu.v29i2.5507","DOIUrl":"https://doi.org/10.21649/akemu.v29i2.5507","url":null,"abstract":"Background: Globally, 80 % of the visual loss is preventable. A major proportion of patients presenting in tertiary care hospitals is that of ophthalmology constituting 20% emergency patients and 18 % outpatient consultations. Objective: To compare the effect of slit lamp teaching versus bedside teaching in ophthalmology residency at a tertiary level teaching hospital. Methodology: This questionnaire based cross sectional survey was conducted after ethical approval at College of Ophthalmology and Allied Vision Sciences/Institute of Ophthalmology, Mayo Hospital, Lahore. Ophthalmology residents from first to fourth year of their training program were included in the study while Consultants, medical officers, fellows and house officers were excluded from the study. A web based close ended questionnaire (Google form) was developed consisting of 13 questions covering different aspects of slit lamp and bedside teaching. Paired sample t-test was applied to check significance among two methods. Results: Upon stratification of the data based on year of residency training, among 3rd year residents, the mean score of bedside teaching was significantly reduced as compared to slit lamp teaching [1.29±0.48 vs 1.86±0.37, t(6) = 2.828, p = 0.03] when they were asked whether practical skills trainings facilitated. Moreover,
 mean score of bedside teaching was significantly reduced as compared to slit lamp teaching among 1st year and 3rd year students when they responded to the question “Is clinical reasoning demonstrated”, 1st year: 1.13± 0.64 vs 1.75±0.46. t(7) = 3.416, p = 0.011 and for 3rd year: 1.14±0.37 vs 2.00±0.00, t(6) = 6.00, p = 0.001. Conclusion: Both slit lamp Teaching and Bedside teaching are vital in ophthalmology residency as they complement each other in making up shortcomings of each other.","PeriodicalId":43918,"journal":{"name":"Annals of King Edward Medical University Lahore Pakistan","volume":"32 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135477362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-27DOI: 10.21649/akemu.v29i2.5506
Bushra Naz, Muhammad Kashif Fida, Muhammad Zohaib Khan, Azkaa Safdar, Aqeel Asghar
Background: The significance and seriousness of COVID-19 vaccination are regarded as a public health emergency for national and international forums. Despite this fact, vaccination readiness is a challenge in young adults due to their belief in general conspiracy theories. Objective: The prime objective of the study was to explore the relationship between vaccination readiness and generic conspiracist beliefs in young adults. Method: A correlational research design was used to conduct this research study. A total sample of 185 young adults (male=83, female=102) aged (20-39 years) fulfilling the inclusion criteria were purposively recruited from different areas of Lahore, Pakistan. An online survey was conducted having demographic information form and standardized questions about vaccination readiness, generic conspiracist beliefs, and health and well-being. The link was sent to the participants through email, WhatsApp, Facebook, Twitter, LinkedIn, and other social media channels. During this survey participants recorded their responses in around ten weeks. Results: Data were analyzed by utilizing SPSS-23 and AMOS-21. The results of correlation analysis revealed that vaccination readiness was inversely associated with generic conspiracist beliefs in young adults. Moreover, generic conspiracist beliefs have a significant negative impact on vaccination readiness. Health and well-being partially mediated the association between generic conspiracist beliefs and vaccination readiness. Conclusion: The authorities should initiate awareness programs to enhance the readiness of the COVID-19 vaccination and also metastasize its effectiveness in young adults. Preventive measures should be taken to eradicate the elements that enhance the generic conspiracist beliefs about vaccination.
{"title":"Vaccination Readiness of COVID-19 and Generic Conspiracist Beliefs Among Young Adults: The Mediated Role of Health and Wellbeing","authors":"Bushra Naz, Muhammad Kashif Fida, Muhammad Zohaib Khan, Azkaa Safdar, Aqeel Asghar","doi":"10.21649/akemu.v29i2.5506","DOIUrl":"https://doi.org/10.21649/akemu.v29i2.5506","url":null,"abstract":"Background: The significance and seriousness of COVID-19 vaccination are regarded as a public health emergency for national and international forums. Despite this fact, vaccination readiness is a challenge in young adults due to their belief in general conspiracy theories. Objective: The prime objective of the study was to explore the relationship between vaccination readiness and generic conspiracist beliefs in young adults. Method: A correlational research design was used to conduct this research study. A total sample of 185 young adults (male=83, female=102) aged (20-39 years) fulfilling the inclusion criteria were purposively recruited from different areas of Lahore, Pakistan. An online survey was conducted having demographic information form and standardized questions about vaccination readiness, generic conspiracist beliefs, and health and well-being. The link was sent to the participants through email, WhatsApp, Facebook, Twitter, LinkedIn, and other social media channels. During this survey participants recorded their responses in around ten weeks. Results: Data were analyzed by utilizing SPSS-23 and AMOS-21. The results of correlation analysis revealed that vaccination readiness was inversely associated with generic conspiracist beliefs in young adults. Moreover, generic conspiracist beliefs have a significant negative impact on vaccination readiness. Health and well-being partially mediated the association between generic conspiracist beliefs and vaccination readiness. Conclusion: The authorities should initiate awareness programs to enhance the readiness of the COVID-19 vaccination and also metastasize its effectiveness in young adults. Preventive measures should be taken to eradicate the elements that enhance the generic conspiracist beliefs about vaccination.","PeriodicalId":43918,"journal":{"name":"Annals of King Edward Medical University Lahore Pakistan","volume":"58 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135471808","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-02DOI: 10.21649/akemu.v29i2.5487
Hilal Bektas Uysal, Murat Duran, Engin Güney, Irfan Yavasoglu, Hulki Meltem Sonmez
Endocrine system originated lymphoma accounts 3% of all extra-nodal lymphoma cases and primary adrenal lymphoma (PAL) constitutes only 0.2% of them (1). In our literature research, there are nearly 250 cases published about PAL, until today. To the best of our knowledge, in addition to this extremely rare incidence of PAL, another accompanying primary malignancy has not been reported in the literature to date. Here, we present the first case of adrenal insufficiency, coexisting with bilateral PAL and follicular thyroid carcinoma.
{"title":"A unique case of adrenal insufficiency coexisting with two primary malignancies","authors":"Hilal Bektas Uysal, Murat Duran, Engin Güney, Irfan Yavasoglu, Hulki Meltem Sonmez","doi":"10.21649/akemu.v29i2.5487","DOIUrl":"https://doi.org/10.21649/akemu.v29i2.5487","url":null,"abstract":"Endocrine system originated lymphoma accounts 3% of all extra-nodal lymphoma cases and primary adrenal lymphoma (PAL) constitutes only 0.2% of them (1). In our literature research, there are nearly 250 cases published about PAL, until today. To the best of our knowledge, in addition to this extremely rare incidence of PAL, another accompanying primary malignancy has not been reported in the literature to date. Here, we present the first case of adrenal insufficiency, coexisting with bilateral PAL and follicular thyroid carcinoma.","PeriodicalId":43918,"journal":{"name":"Annals of King Edward Medical University Lahore Pakistan","volume":"185 1","pages":""},"PeriodicalIF":0.4,"publicationDate":"2023-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80569592","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-02DOI: 10.21649/akemu.v29i2.5483
Sana Arif, Nabeela Riaz, Ehsah-ul- Haq, H. Nasir
Odontomas are odontogenic tumors in which complete functional discrepancy of ameloblasts or odontoblasts occur with the development of enamel and dentine in an irregular arrangement due to lack of association of these cells to reach usual state of morphodifferentiation. Multiple hybrid odontomas present as many complex or compound odontomas involving one to all four quadrants of jaws. this present case is of a female aged 12 years who presented with mild pain and swelling in the right body of mandible for 1 year. After initial clinical and radiographic assessment, a tentative diagnosis of multiple hybrid odontomas involving all four quadrants of jaws was made. Surgical excision of the lesion which was causing facial deformity was performed. Excisional biopsy report verified the clinical diagnosis. This case report describes the first unique case of multiple hybrid odontomas involving all four quadrants of jaws presented in last five years' literature.
{"title":"Mutiple Hybrid Odontomas Involving All Four Quadrants of Jaws: A Rare Case Report","authors":"Sana Arif, Nabeela Riaz, Ehsah-ul- Haq, H. Nasir","doi":"10.21649/akemu.v29i2.5483","DOIUrl":"https://doi.org/10.21649/akemu.v29i2.5483","url":null,"abstract":"Odontomas are odontogenic tumors in which complete functional discrepancy of ameloblasts or odontoblasts occur with the development of enamel and dentine in an irregular arrangement due to lack of association of these cells to reach usual state of morphodifferentiation. Multiple hybrid odontomas present as many complex or compound odontomas involving one to all four quadrants of jaws. this present case is of a female aged 12 years who presented with mild pain and swelling in the right body of mandible for 1 year. After initial clinical and radiographic assessment, a tentative diagnosis of multiple hybrid odontomas involving all four quadrants of jaws was made. Surgical excision of the lesion which was causing facial deformity was performed. Excisional \u0000biopsy report verified the clinical diagnosis. This case report describes the first unique case of multiple hybrid odontomas involving all four quadrants of jaws presented in last five years' literature.","PeriodicalId":43918,"journal":{"name":"Annals of King Edward Medical University Lahore Pakistan","volume":"18 3 1","pages":""},"PeriodicalIF":0.4,"publicationDate":"2023-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82816177","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-02DOI: 10.21649/akemu.v29i2.5484
J. Khan, A. Shah, Ayesha Qaisar
Cirrhosis of liver has been the centre of attention for all the gastroenterologists for decades in terms of different manifestations and complications and at the same time very challenging to manage.1 There has been some success but not complete eradication of the disease as the risk factors including chronic hepatitis B, C, autoimmune hepatitis , Wilson disease, and most importantly alcohol especially in the western countries remain a daunting task to treat.2 Those who are compliant to treatment are relatively easy to address. Without treatment the complications are devastating leading to the death of the patient.
{"title":"Management of Cirrhotic: Double Edged Sword","authors":"J. Khan, A. Shah, Ayesha Qaisar","doi":"10.21649/akemu.v29i2.5484","DOIUrl":"https://doi.org/10.21649/akemu.v29i2.5484","url":null,"abstract":"Cirrhosis of liver has been the centre of attention for all the gastroenterologists for decades in terms of different manifestations and complications and at the same time very challenging to manage.1 There has been some success but not complete eradication of the \u0000disease as the risk factors including chronic hepatitis B, C, autoimmune hepatitis , Wilson disease, and most importantly alcohol especially in the western countries remain a daunting task to treat.2 Those who are compliant to treatment are relatively easy to address. Without treatment the complications are devastating leading to the death of the patient.","PeriodicalId":43918,"journal":{"name":"Annals of King Edward Medical University Lahore Pakistan","volume":"46 1","pages":""},"PeriodicalIF":0.4,"publicationDate":"2023-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85086754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-02DOI: 10.21649/akemu.v29i2.5486
Tooba Fatima, Yaser Imran, M. Ghias, Samara Siddique, Bilquis Shabbir, Asif Islam, Tazeen Nazar, Bilal Aziz
Background: The peripheral joints are particularly vulnerable to the autoimmune disease rheumatoid arthritis. Patients with rheumatoid arthritis often exhibit symptoms of metabolic syndrome. Metabolic syndrome in rheumatoid arthritis is connected with increased morbidity and death. Objective: This study aimed to examine whether or not rheumatoid arthritis patients who had high levels of disease activity also developed metabolic syndrome. Methods: The cohort study was conducted on 64 patients (32 in each group), included via Non-probability convenient sampling. Disease activity score of 28 joints (DAS-28 score) was used to assess the severity of disease activity in patients of rheumatoid arthritis and two groups were developed i.e. group I with score ≥3.2 and group II with score
{"title":"Association of Severe Disease Activity with Metabolic Syndrome in Patients with Early Rheumatoid Arthritis: A Cohort Study from Tertiary Care Hospital of Pakistan","authors":"Tooba Fatima, Yaser Imran, M. Ghias, Samara Siddique, Bilquis Shabbir, Asif Islam, Tazeen Nazar, Bilal Aziz","doi":"10.21649/akemu.v29i2.5486","DOIUrl":"https://doi.org/10.21649/akemu.v29i2.5486","url":null,"abstract":"Background: The peripheral joints are particularly vulnerable to the autoimmune disease rheumatoid arthritis. Patients with rheumatoid arthritis often exhibit symptoms of metabolic syndrome. Metabolic syndrome in rheumatoid arthritis is connected with increased morbidity and death. Objective: This study aimed to examine whether or not rheumatoid arthritis patients who had high levels of disease activity also developed metabolic syndrome. Methods: The cohort study was conducted on 64 patients (32 in each group), included via Non-probability convenient sampling. Disease activity score of 28 joints (DAS-28 score) was used to assess the severity of disease activity in patients of rheumatoid arthritis and two groups were developed i.e. group I with score ≥3.2 and group II with score","PeriodicalId":43918,"journal":{"name":"Annals of King Edward Medical University Lahore Pakistan","volume":"19 1","pages":""},"PeriodicalIF":0.4,"publicationDate":"2023-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75233538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-02DOI: 10.21649/akemu.v29i2.5485
M. Bukhari
Writing for a biomedical journal is an important part of completing a research project. It is vital to publish original articles or other types of articles in various medical journals. This can be a challenging process, and it requires a sense of responsibility. The process starts with conceiving an idea, forming and conducting the research, and writing about the results, before finally getting it published. Before beginning to write a paper, the language must be properly structured and technical details must be included. Additionally, a cover letter must is sent to the journal's chief editor, mentioning any ethical considerations.
{"title":"Writing an Effective Medical Manuscript and Avoiding Errors for Smooth Publication","authors":"M. Bukhari","doi":"10.21649/akemu.v29i2.5485","DOIUrl":"https://doi.org/10.21649/akemu.v29i2.5485","url":null,"abstract":"Writing for a biomedical journal is an important part of completing a research project. It is vital to publish original articles or other types of articles in various medical journals. This can be a challenging process, and it requires a sense of responsibility. The process starts with conceiving an idea, forming and conducting the research, and writing about the results, before finally getting it published. Before beginning to write a paper, the language must be properly structured and technical details must be included. Additionally, a cover letter must is sent to the journal's chief editor, mentioning any ethical considerations.","PeriodicalId":43918,"journal":{"name":"Annals of King Edward Medical University Lahore Pakistan","volume":"8 1","pages":""},"PeriodicalIF":0.4,"publicationDate":"2023-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78263563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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