Photodynamic Therapy Using 5-Aminolevulinic Acid for Cervical Intraepithelial Neoplasia

美香 水野
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Abstract

Cervical intraepithelial neoplasia is a premalignancy of cervical cancer, and is not a rare disease. Standard treatment for cervical intraepithelial neoplasia (CIN) 3 is surgery, but this method has been shown to lead to premature birth. Photodynamic therapy (PDT) is a minimally invasive treatment option for carcinoma in situ (CIS). Several authors have reported the efficacy of conventional PDT, but the diffusion rate continues to be set low, due to concerns regarding side effects and the need for prolonged hospitalization. We have conducted an innovative clinical trial for patients with CIN using 5-Aminolevulinic acid (5ALA) and LED technology.
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5-氨基乙酰丙酸光动力疗法治疗宫颈上皮内瘤变
宫颈上皮内瘤变是宫颈癌的一种恶性前病变,并不罕见。宫颈上皮内瘤变(CIN)的标准治疗是手术,但这种方法已被证明会导致早产。光动力疗法(PDT)是原位癌(CIS)的一种微创治疗选择。一些作者报道了传统PDT的疗效,但由于担心副作用和需要长时间住院,扩散率仍然设定得很低。我们利用5-氨基乙酰丙酸(5ALA)和LED技术对CIN患者进行了一项创新的临床试验。
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Program 第34回日本レーザー医学会西日本大会(旧:関西支部会) 第34回日本レーザー治療学会 総会・学術大会開催のご案内 The 33<sup>rd</sup> Annual Meeting of the Japan Photodynamic Association The 19<sup>th</sup> Japan Photodynamic Neurosurgical Society The 35<sup>th</sup> Annual Meeting of Japanese Society for Laser Dentistry 選奨委員会からのお知らせ
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