Marine biomolecules: a promising approach in therapy and biotechnology

Asmaa Chbel, Aurelio Serrano Delgado, A. Soukri, B. E. Khalfi
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引用次数: 5

Abstract

The marine environment is characterized by a wide diversity of microorganisms among which marine bacteria. To insure their survival in hostile conditions where they face high competition with pathogenic microorganisms, they produce various kinds of bioactive molecules within biofilms with unique structural and functional features. As example: marine peptides which provide a broad spectrum of antimicrobial, antitumoral, antiviral and anti-inflammatory activities, in addition to marine exopolysaccharides showing antifouling and antifungal activities, immunomodulatory properties, emulsion stabilization capacity with other various potentials. Some biofilms have shown a beneficial role for aquaculture, among which enhancement of growth performance and improvement of water quality, while others are threatening not only aquaculture and maritime fields, but also medicine and food industry. Thus, marine bioactive compounds are promising preventing agents for the establishment and growth of fouling microorganisms, which may be useful in different fields in order to decrease economic losses and avoid foodborne illnesses. DOI: http://dx.doi.org/10.5281/zenodo.4384158
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海洋生物分子:治疗和生物技术的一个有前途的方法
海洋环境的特点是微生物种类繁多,其中包括海洋细菌。为了确保它们在与病原微生物激烈竞争的恶劣条件下生存,它们在生物膜内产生各种具有独特结构和功能特征的生物活性分子。例如:具有广谱抗菌、抗肿瘤、抗病毒和抗炎活性的海洋多肽,以及具有抗污染和抗真菌活性、免疫调节特性、乳液稳定能力等多种潜力的海洋外多糖。有些生物膜对水产养殖具有提高生长性能、改善水质等有益作用,而另一些生物膜不仅对水产养殖和海洋领域构成威胁,还对医药和食品工业构成威胁。因此,海洋生物活性化合物是一种很有前景的防止污染微生物滋生和生长的药剂,在减少经济损失和避免食源性疾病方面具有重要的应用前景。DOI: http://dx.doi.org/10.5281/zenodo.4384158
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