Current status of surgical diagnosis and treatment of pulmonary malignant ground glass nodules

Liang Cheng, Zhong Jiang, Wei Gao, Yongsheng Zhao, M. Fu
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Abstract

In recent years, with the development of imaging technology, more and more ground-glass Nodule (GGN) in the lungs have been discovered. After GGN is detected, it should be further judged whether it is benign or malignant by combining with existing inspection methods. Common diagnostic and examination methods include PET/CT, fiberoptic bronchoscopy, CT-guided puncture biopsy and High Resolution CT (HRCT), each of them with its own advantages and disadvantages. For GGN with high malignant risk, minimally invasive surgical intervention is needed to prevent the progress of the disease. The hot issues of surgical treatment include the selection of minimally invasive surgical methods, the precise positioning of GGN in the lung, the accuracy and limitations of intraoperative freezing examination, lymph node dissection of GGN, and postoperative follow-up of malignant GGN diagnosed as cancer. Under the premise that surgical diagnosis and treatment play an increasingly important role in the management of GGN, this paper will review the existing GGN related studies and make a summary of the surgical diagnosis and treatment of malignant GGN.
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肺恶性磨玻璃结节的外科诊断与治疗现状
近年来,随着影像技术的发展,越来越多的肺部磨玻璃结节(GGN)被发现。检测到GGN后,应结合现有的检查方法进一步判断其是良性还是恶性。常用的诊断和检查方法有PET/CT、纤维支气管镜检查、CT引导穿刺活检和高分辨率CT (HRCT),各有优缺点。对于恶性风险高的GGN,需要微创手术干预,防止病情发展。手术治疗的热点问题包括微创手术方式的选择、GGN在肺部的精确定位、术中冷冻检查的准确性和局限性、GGN淋巴结清扫、恶性GGN诊断为癌症的术后随访等。在手术诊断和治疗在GGN的治疗中发挥越来越重要的作用的前提下,本文将回顾已有的GGN相关研究,对恶性GGN的手术诊断和治疗进行总结。
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