Assessment Biochemical Parameters Role in Women with Polycystic Ovary Syndrome (PCOS) in Nineveh Governorate

Abstract

Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders in female reproductive age, it is associated with metabolic disorder, oxidative stress and infertility. This study amid to show the effect of PCOS and obesity on a number of biochemical parameters in serum of 70 patients which age ranged (15-45) years attending Al-khansa hospital and private laboratories in Nineveh governorate They were diagnosed as PCOS by gynecologists, obstetricians and infertility doctors, 50 of healthy female with the same ages of patient were used as a control group for comparison. The results showed significant increase (P≤0.01) in concentration of Glucose, Insulin, Insulin resistance HOMA-IR, Triglyceride, Cholesterol, Low density lipoprotein LDL, very low-density lipoprotein VLDL, with non-significant decrease in High density lipoprotein HDL compared to control group. When comparing the previously mentioned parameters in serum of obese PCOS (BMI>30) with non-obese PCOS (BMI<30) we found significant increase (P≤0.05) in these parameters in obese more than in non-obese patient.