Green synthesis of silver nanoparticles from Morinda tinctoria Roxb and scrutiny of its multi facet on biomedical applications

G. Paramasivam, R. Kannan, S. Paulraj, J. Pandiarajan
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引用次数: 5

Abstract

Objective : This research work focus on synthesis of silver nanoparticles from Morinda tinctoria Roxb leaves. The synthesis of nanoparticles from biological processes is evolving a new era of research interests in nanotechnology. Silver nanoparticles are usually synthesized by chemicals. M. tinctoria Roxb leaves are reputed plant in traditional system of medicine and it is used for the treatment of illness such as arthritis, cancer, gastric ulcer and other heart disease etc. Methods : The present study the leaves were collected, air dried and extract silver nanoparticles. The extract was subjected to characterization, antimicrobial activity, antidiabetic and anticancer activity using M. tinctoria Roxb leaves following standard procedures. Results : Silver nanoparticles study showed the evaluation of antioxidant and anticancer activity of M. tinctoria Roxb. Antioxidant activities were done using DPPH antioxidant assay and hydrogen peroxide assay. The anticancer study was conducted to evaluate the in-vitro anticancer activity of green synthesized nanoparticles using human hepatic carcinoma cell lines (HepG2). Conclusions : The leaf extract of silver nanoparticle evaluation showed higher antioxidant activity and anticancer activity in M. tinctoria Roxb.
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巴戟达纳米银的绿色合成及其在生物医学上的应用
目的:研究从巴戟天叶中合成纳米银的工艺。从生物过程合成纳米粒子是纳米技术研究的一个新领域。银纳米颗粒通常是由化学物质合成的。黄芪叶是传统医学中享有盛誉的植物,用于治疗关节炎、癌症、胃溃疡和其他心脏病等疾病。方法:采用风干法提取银纳米粒子。采用标准方法,对提取液进行表征、抑菌活性、抗糖尿病活性和抗癌活性研究。结果:银纳米颗粒研究表明,银纳米颗粒具有抗氧化和抗癌活性。采用DPPH抗氧化法和过氧化氢法测定其抗氧化活性。以人肝癌细胞株HepG2为实验对象,研究了绿色合成纳米颗粒的体外抗癌活性。结论:银纳米颗粒叶提取物具有较高的抗氧化活性和抗癌活性。
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