Efficacy of the bioactive compounds of medicinal importance in the leaves of Lantana camara L. and Andrographis paniculata (Burm. f.) Wall. ex Nees.

Abstract

The present study includes the phytochemical detection and antimicrobial activity of the leaves of Lantana camara L. and Andrographis paniculata (Burm. f.) Wall. ex Nees. Phytochemical screening of the leaf extract of leaves shade dried indicated the presence of flavonoids, terpenoids, tannins, alkaloids, steroids and glycosides. The antibacterial activity of ethanolic and aqueous extracts of leaves of Lantana camara and Andrographis paniculata were evaluated against the human pathogenic bacteria like Staphylococcus aureus and Pseudomonas aeruginosa by well diffusion method. Among the extracts analysed ethanolic extracts showed promising results whereas aqueous extracts did not report any zone of inhibition. The ethanol leaf extract (200μg/ml) showed maximum inhibition against Pseudomonas aeruginosa (16mm) and Staphylococcus aureus (16mm). Phytochemical tests carried out showed that the antibacterial activity of plant Lantana camara and Andrographis paniculata leaves was due to the presence of phytochemical compounds present in it.