COVID-19: A Multipeak SIR Based Model for Learning Waves and Optimizing Testing

G. Perakis, Divya Singhvi, O. Skali Lami, Leann Thayaparan
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引用次数: 5

Abstract

One of the greatest challenges of the COVID-19 pandemic has been the way evolving regulation, information and sentiment has driven waves of the disease. Traditional epidemiology models, such as the SIR model, are not equipped to handle these behavioral based changes. We propose a novel multipeak SIR model, which can detect and model the waves of the disease. We bring together the SIR model’s compartmental structure with a change-point detection martingale process to identify new waves. We create a dynamic process where new waves can be flagged and learned in real time. We use this approach to extend the traditional SEIRD model into a multipeak SEIRD model and test it on forecasting COVID-19 cases from the John Hopkins University dataset for states in the United States. We found that compared to the traditional SEIRD model, the multipeak SEIRD model improves MAPE by 10%-15% for the United States, and by 25%-40% in the specific regions that were hit by the multiple waves. We then pair this model with an optimization model for testing, which is critical in managing the epidemic and which significantly outperforms alternative testing strategies (more than 57% in detection rate). We show how to prioritize symptomatic, asymptomatic and contact tracing populations, most interestingly when balancing testing early to reach contact tracers and saving tests for later when the epidemic is worse.
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COVID-19:基于多峰SIR的学习波和优化测试模型
COVID-19大流行的最大挑战之一是不断变化的监管、信息和情绪如何推动了疾病的浪潮。传统的流行病学模型,如SIR模型,无法处理这些基于行为的变化。我们提出了一种新的多峰SIR模型,可以检测和建模疾病的波。我们将SIR模型的隔室结构与变化点检测鞅过程结合起来,以识别新波。我们创建了一个动态的过程,新的浪潮可以被标记和实时学习。我们使用这种方法将传统的SEIRD模型扩展为多峰SEIRD模型,并在美国约翰霍普金斯大学数据集中对COVID-19病例的预测进行了测试。我们发现,与传统的SEIRD模型相比,多峰SEIRD模型在美国将MAPE提高了10%-15%,在受到多波袭击的特定区域将MAPE提高了25%-40%。然后,我们将该模型与检测的优化模型配对,这对于管理流行病至关重要,并且显著优于其他检测策略(检出率超过57%)。我们展示了如何优先考虑有症状、无症状和接触者追踪人群,最有趣的是,在平衡早期检测以获得接触者追踪者和将检测留到疫情恶化时进行时。
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