{"title":"IRM et SRM 1H-1D in vivo à 7 T d’un modèle de régénération musculaire sur la souris","authors":"Catherine Sébrié, Brigitte Gillet, Jean-Claude Belœil","doi":"10.1016/S1387-1609(01)01324-X","DOIUrl":null,"url":null,"abstract":"<div><p>In this study, skeletal muscle degeneration–regeneration, induced by notexin (a myotoxic substance) injection is studied by Magnetic Resonance Imaging (MRI) and by histological cuts (hematoxylin/eosin and Evans blue colorations). Comparison between MR images and histological cuts results (necrosis, myoblasts replication and fusion) permits MR images interpretation. From day 0 to day 13 after notexin injection, injected zone images are very different from those realized in healthy muscles. Preliminary localized 1D <sup>1</sup>H-MRS (Magnetic Resonance Spectroscopy) study is also reported.</p></div>","PeriodicalId":100305,"journal":{"name":"Comptes Rendus de l'Académie des Sciences - Series IIC - Chemistry","volume":"4 10","pages":"Pages 783-787"},"PeriodicalIF":0.0000,"publicationDate":"2001-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1387-1609(01)01324-X","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Comptes Rendus de l'Académie des Sciences - Series IIC - Chemistry","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S138716090101324X","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
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Abstract
In this study, skeletal muscle degeneration–regeneration, induced by notexin (a myotoxic substance) injection is studied by Magnetic Resonance Imaging (MRI) and by histological cuts (hematoxylin/eosin and Evans blue colorations). Comparison between MR images and histological cuts results (necrosis, myoblasts replication and fusion) permits MR images interpretation. From day 0 to day 13 after notexin injection, injected zone images are very different from those realized in healthy muscles. Preliminary localized 1D 1H-MRS (Magnetic Resonance Spectroscopy) study is also reported.
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