Development of the method of surgical correction of insolvency bauginia damper-Experience of 600 operations

Abstract

reflux in most people. The predominance of sensory neurons in the innervation of the ileocecal region indicates that the ileocecal valve is a highly sensitive formation of the human intestine. According to LG Peretz [1975], 1ml of the small intestine contains up to 5000 microbes, and 1g of the contents of the large intestine contains about 30-40 billion. With the loss of the barrier function of the Bauhinia valve, colonization of the small intestine by foreign microbes from another habitat occurs with the development of dysbiosis1 and certain pathological consequences.2 The study of the content of enzymes in the feces of patients with reflux enteritis showed the presence of hyperfermentosis, i.e., an increased content of enterokinase, alkaline phosphatase, as well as bile acids, pancreatic enzymes, and stomach enzymes. This fecal hyperfermentosis is a consequence of incomplete deactivation of intestinal enzymes, deconjugation of primary bile acids. Fecal hyperfermentosis, as well as the presence of primary bile acids in the large intestine, especially in its left half, serves as a trigger for spastic colitis, especially left-sided.3 M. Brotman [348] found that about 95% of bile acids are normally absorbed in the ileum, which re-enter the liver, GG Nemsadze & EP Rybin4 found in a group of 192 patients with colon cancer a significant increase in the excretion of bile acids with the failure of the Bauhinia valve in comparison with its normal function. Indirect data on the possible role of NBZ in increasing the excretion of bile acids were obtained by analyzing the characteristics of the metabolism of bile acids in the enterohepatic cycle.5 Some authors suggest that, through the formation of carcinogenic substances from bile acids, bacteroids may contribute to an increased incidence of colon cancer.6 Other authors7 definitely believe that “the elimination of NBZ and the use of anti reflux anastomosis open up the possibility of surgical prevention of precancerous diseases and colonic cancer.