The Indication of Primary ICSI

Emiko Takaoka, Akiko Onitsukawaki, H. Tokunaga, Reiko Numata, Tetsuya Nomura
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Abstract

the indication of primary ICSI. In 639 cycles (356 cases) of conventional IVF, we examined the fertilization rate and pregnancy rate upon following items. Those were appearance and concentration of sperm, female age, and picked up oocyte. In the study of correlation between sperm concentration and rate of fertilization or pregnancy, the cases of sperm concentration less than 10 × 10 6 /ml were fertilized only 13.3% (18/135) or no cases were got pregnant (0/21). in the study of correlation between sperm motility rate and rate of fertilization or pregnancy, even in cases of motility rate less than 20%, fertilization rate was 33% (43/130) and pregnant rate was 19% (4/21). We also considered the sperm concentration after the swim up cases. In the cases sperm concentration less than 1 × 10 6 /ml, fertilization rate was only 2.3% (2/86) or no cases got pregnant (0/13). We could definite correlation between female ages or quantity of picked up oocyte and rate of fertilization and pregnancy respectively. that these are not applied to the indication of primary ICSI. We that the indication of primary ICSI should be on the sperm concentration and the numerical numbers were less than 10 × 10 6 /ml for ordinary cases and less than 1 × 10 6 /ml for after the swim up
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原发性ICSI的适应证
原发性ICSI的指征。我们对639个周期(356例)的常规体外受精进行了受精率和受孕率的检测。这些是精子的外观和浓度,女性的年龄,和卵母细胞。在精子浓度与受精率或受孕率的相关性研究中,精子浓度低于10 × 10 6 /ml的患者受精率仅为13.3%(18/135)或无患者受孕(0/21)。在精子动率与受精率或受孕率的相关性研究中,即使在动率低于20%的情况下,受精率为33%(43/130),受孕率为19%(4/21)。我们还考虑了游泳后的精子浓度。精子浓度低于1 × 106 /ml者受精率仅为2.3%(2/86)或无妊娠(0/13)。可以确定女性年龄、卵母细胞捡取量与受精率和受孕率的相关性。这些不适用于原发性ICSI的适应症。我们认为初次ICSI的指征应以精子浓度为标准,正常情况精子浓度小于10 × 10.6 /ml,游泳后精子浓度小于1 × 10.6 /ml
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