The Post-Discharge Growth of Very Low Birth Weight Preterm Infants

Tuba Ozdemir, A. Akcan, M. Turkmen
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Abstract

OBJECTIVE: In the present study, we investigate the growth characteristics of very low birth weight premature infants of up to two years corrected age, considering the factors affecting growth and catch-up growth time. STUDY DESIGN: The demographic data, clinical features, and comorbidities of 77 preterm infants with birth weights of less than or equal to 1.500 g were examined, the infants’ growth statuses in the 40th gestational week (gw) and at 6, 12, 18 and 24 months the corrected age, including their weight, height and head circumference, were evaluated. RESULTS: The findings revealed that very low birth weight infants should be closely monitored either during their stay in the Neonatal Intensive Care Unit, or for up to 6 months corrected age, paying particular attention to growth data, and the appropriate supportive treatment should be administered. The applied support process is influential on the future somatic growth of preterm infants. It was noted in the study that bronchopulmonary dysplasia, proven sepsis, respiratory distress syndrome, steroid treatment for more than three days, patent ductus arteriosus, and ibuprofen treatment seemed to affect somatic growth negatively. CONCLUSION: Small for gestational age newborns were found to catch up with appropriate for gestational age newborns at 2 years corrected age in terms of growth, although the percentage of catch-up growth during follow-up at the 40thgw, and at the 6th, 12th and 18th months was lower than that of appropriate for gestational age newborns.
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极低出生体重早产儿的出院后生长
目的:研究2岁以下极低出生体重早产儿的生长特征,考虑影响生长的因素和追赶生长时间。研究设计:研究77例出生体重小于等于1.500 g的早产儿的人口统计学资料、临床特征及合并症,评估婴儿在第40孕周(gw)及校正年龄6、12、18、24个月时的生长状况,包括体重、身高和头围。结果:研究结果显示,极低出生体重儿在新生儿重症监护病房住院期间或6个月矫正年龄前都应密切监测,特别注意生长数据,并应给予适当的支持治疗。应用支持过程对早产儿未来的躯体发育有影响。研究中指出,支气管肺发育不良、确诊的败血症、呼吸窘迫综合征、类固醇治疗超过三天、动脉导管未闭和布洛芬治疗似乎对躯体生长有负面影响。结论:小胎龄儿在校正年龄2岁时生长赶上适胎龄儿,但随访时第40胎龄、第6、12、18个月的生长赶上率低于适胎龄儿。
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