Rongrong Zhang, Chunqing Xie, Yayun Zhu, Liangjun Pan, Changying Yang
{"title":"The Electrochemical Impedance Recognition for Two Heme Proteins on dsDNA/PGA/GCE","authors":"Rongrong Zhang, Chunqing Xie, Yayun Zhu, Liangjun Pan, Changying Yang","doi":"10.1109/ICBEB.2012.13","DOIUrl":null,"url":null,"abstract":"A DNA-modified electrode was fabricated by the way of electrode modifying, namely the polymerisation-covalently bonding, for studying the recognition of DNA to heme protein. Electrochemical Impedence Resistance (EIS) showed that electron transfer resistance increased with the adding of Hemoglobin (Hb) and Cytochrome c (Cyt c). Reaction constant of Hb and DNA is K=1.13×10<sup>5</sup> L-mol<sup>-1</sup>, and K=4.08×10<sup>5</sup> L-mol<sup>-1</sup> for Cyt c, indicating that DNA-modified electrode can well recognize Hb and Cyt c.","PeriodicalId":6374,"journal":{"name":"2012 International Conference on Biomedical Engineering and Biotechnology","volume":"107 1","pages":"925-928"},"PeriodicalIF":0.0000,"publicationDate":"2012-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"2012 International Conference on Biomedical Engineering and Biotechnology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/ICBEB.2012.13","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
A DNA-modified electrode was fabricated by the way of electrode modifying, namely the polymerisation-covalently bonding, for studying the recognition of DNA to heme protein. Electrochemical Impedence Resistance (EIS) showed that electron transfer resistance increased with the adding of Hemoglobin (Hb) and Cytochrome c (Cyt c). Reaction constant of Hb and DNA is K=1.13×105 L-mol-1, and K=4.08×105 L-mol-1 for Cyt c, indicating that DNA-modified electrode can well recognize Hb and Cyt c.
京公网安备 11010802042870号
京ICP备2023020795号-1
分享
求助内容：
应助结果提醒方式：
扫码关注我们
