Susceptibility of MMP3 gene polymorphism to coronary artery disease: A meta-analysis.

IF 2 4区 医学 Q4 BIOCHEMISTRY & MOLECULAR BIOLOGY Journal of Medical Biochemistry Pub Date : 2023-10-27 DOI:10.5937/jomb0-43315
Liu Wenwang
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Abstract

Background: Conclusions on susceptibility of MMP3-1612 5A/6A to morbid risk of coronary artery disease (CAD) are controversial. This meta-analysis aims to obtain the accurate relationship between them.

Methods: Relevant literatures on susceptibility of MMP3-1612 5A/6A to morbid risk of CAD published before July 2019 were searched in PubMed, Web of Science, Cochrane Library, CNKI, VIP and Wanfang. Data were extracted from eligible literatures and analyzed by RevMan5.3 and STATA12.0 for calculating OR and corresponding 95% CI. Study selection: A total of 18 literatures reporting MMP3-1612 5A/6A and CAD were enrolled. Data extraction was conducted by two researches independently. Any disagreement was solved by the third research.

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MMP3基因多态性对冠心病的易感性:荟萃分析
背景:关于MMP3-1612 5A/6A与冠状动脉疾病(CAD)发病风险易感性的结论存在争议。本荟萃分析旨在获得它们之间的准确关系:在PubMed、Web of Science、Cochrane Library、CNKI、VIP和万方数据库中检索2019年7月之前发表的关于MMP3-1612 5A/6A与CAD发病风险易感性的相关文献。从符合条件的文献中提取数据,用RevMan5.3和STATA12.0进行分析,计算OR和相应的95%CI。研究选择:共有 18 篇文献报道了 MMP3-1612 5A/6A 与 CAD 的关系。数据提取由两名研究人员独立完成。如有分歧,由第三位研究人员解决。
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来源期刊
Journal of Medical Biochemistry
Journal of Medical Biochemistry BIOCHEMISTRY & MOLECULAR BIOLOGY-
CiteScore
3.00
自引率
12.00%
发文量
60
审稿时长
>12 weeks
期刊介绍: The JOURNAL OF MEDICAL BIOCHEMISTRY (J MED BIOCHEM) is the official journal of the Society of Medical Biochemists of Serbia with international peer-review. Papers are independently reviewed by at least two reviewers selected by the Editors as Blind Peer Reviews. The Journal of Medical Biochemistry is published quarterly. The Journal publishes original scientific and specialized articles on all aspects of clinical and medical biochemistry, molecular medicine, clinical hematology and coagulation, clinical immunology and autoimmunity, clinical microbiology, virology, clinical genomics and molecular biology, genetic epidemiology, drug measurement, evaluation of diagnostic markers, new reagents and laboratory equipment, reference materials and methods, reference values, laboratory organization, automation, quality control, clinical metrology, all related scientific disciplines where chemistry, biochemistry, molecular biology and immunochemistry deal with the study of normal and pathologic processes in human beings.
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