Genomic Analysis of fgf in zebra Fish (Danio Rerio)

Ayesha T Tahir
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Abstract

FGFs are abbreviated as “Fibroblast growth factors”. These "FGFs" are the "secreted “development factors of polypeptide. The "signaling" scheme of FGFs is actually the vital part which "plays" a significant role in many processes of development in vertebrates. The humans also have FGFs family. This family comprises of 22 members. On the other hand, zebra fish family has 16 members while eleven more zebra fish fgf were identified by homo-logy based search. This search was conducted in zebra fish genome and cDNA databases. By calculating additional member’s fgf family of zebra fish now consist of 27 members at least. By the conduction of polygenetic processes and gene location analyses, we identified relationships between human FGFs genes and zebra fish Fgf genes. This paper also evaluates and represents the phylogenetic information of fgf zebra fish family.
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斑马鱼fgf的基因组分析
FGFs缩写为“成纤维细胞生长因子”。这些“fgf”是多肽的“分泌”发育因子。FGFs的“信号”机制实际上是至关重要的一部分,在脊椎动物的许多发育过程中“起着”重要作用。人类也有fgf家族。这个家庭由22个成员组成。另一方面,斑马鱼家族有16个成员,通过同源性搜索鉴定出11个斑马鱼fgf。本研究在斑马鱼基因组和cDNA数据库中进行。通过计算额外的成员,斑马鱼的fgf家族现在至少由27个成员组成。通过多基因过程和基因定位分析,我们确定了人类Fgf基因与斑马鱼Fgf基因之间的关系。本文还对fgf斑马鱼科的系统发育信息进行了评价和描述。
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