Burkholderia pseudomallei – The malicious invader causing orbital cellulitis !!!

I. Karthiga, Veni Sigamani, S. Bhat, Harish Kumar Aravind
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Abstract

This case report represents an unusual presentation of Melioidosis presenting as orbital cellulitis. Orbital cellulitis is an acute infection of the eye, commonly caused by Staphylococcal, Streptococcal species and also by fungi. Here we report a case of a 57 year old male who was a diabetic and hypertensive presented with fever, protrusion of right eyeball with sudden onset of defective vision. On examination right eye visual acuity was light perception with relative afferent pupillary defect. Proptosis, chemosis and total ophthalmoplegia were present. Routine investigation revealed leucocytosis. Conjunctival swab culture was negative whereas blood culture revealed Burkholderia pseudomallei. On further work up ultrasound abdomen showed splenic abscess. Even with effective treatment with IV antibiotics patient didn’t improve and succumbed to this disease. Ocular involvement in melioidosis is rare but can lead to devastating outcomes. This case represents the highly virulent nature of this organism which rarely presents with ocular involvement as primary presentation.
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假性伯克霍尔德菌——引起眼眶蜂窝织炎的恶意入侵者!!
本病例报告是一罕见的类鼻疽,表现为眼眶蜂窝织炎。眼眶蜂窝织炎是一种眼部的急性感染,通常由葡萄球菌、链球菌和真菌引起。我们在此报告一位57岁男性糖尿病及高血压患者,以发烧、右眼球突出及突发性视力缺陷为主要表现。检查右眼视敏度为光感,瞳孔相对传入缺损。主要表现为眼球突出、化脓和全眼麻痹。常规检查显示白细胞增多。结膜拭子培养为阴性,而血培养显示假马利氏伯克氏菌。进一步腹部超声检查显示脾脓肿。即使通过静脉注射抗生素有效治疗,患者也没有好转,最终死于此病。类鼻疽病的眼部受累是罕见的,但可导致毁灭性的结果。这个病例代表了这种生物的高毒性,很少以眼部受累为主要表现。
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