{"title":"BRINE SHRIMP LETHALITY BIOASSAY OF GLAUCIUM GRANDIFLORUM VAR. GRANDIFLORUM","authors":"A. Sari, Ç. Ünsal, I. Sari, I. Sarioğlu","doi":"10.16883/JFPIU.17946","DOIUrl":null,"url":null,"abstract":"Turkiye'nin 3 farkli bolgesinden toplanan Glaucium grandiflorum Boiss. et Huet var. grandiflorum orneklerinin toprak ustu kisimlarindan elde edilen alkaloit ekstreleri ve bu ekstrelerden elde edilen major alkaloitler allokriptopin, protopIn, (+)-izokoridin, (+)-korIdin uzerinde brIne shrimp lethality testi yapilarak sitotoksisiteleri Incelenmistir. Glaucium grandiflorum var. grandiflorum turunun 3 ornegi de onemli oranda sitotoksik aktIvite gostermistir. Allokriptopin, protopin, (+)-izokoridin, (+)-koridin sirasiyla 15.92, 37.51, 237.24, 75.95 LC50 degerleri ile kuvvetli sitotoksik aktivite gostemistir.","PeriodicalId":15850,"journal":{"name":"Journal of Faculty Pharmacy of Istanbul University","volume":"25 1","pages":"57-60"},"PeriodicalIF":0.0000,"publicationDate":"2007-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Faculty Pharmacy of Istanbul University","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.16883/JFPIU.17946","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Turkiye'nin 3 farkli bolgesinden toplanan Glaucium grandiflorum Boiss. et Huet var. grandiflorum orneklerinin toprak ustu kisimlarindan elde edilen alkaloit ekstreleri ve bu ekstrelerden elde edilen major alkaloitler allokriptopin, protopIn, (+)-izokoridin, (+)-korIdin uzerinde brIne shrimp lethality testi yapilarak sitotoksisiteleri Incelenmistir. Glaucium grandiflorum var. grandiflorum turunun 3 ornegi de onemli oranda sitotoksik aktIvite gostermistir. Allokriptopin, protopin, (+)-izokoridin, (+)-koridin sirasiyla 15.92, 37.51, 237.24, 75.95 LC50 degerleri ile kuvvetli sitotoksik aktivite gostemistir.
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