Herbal Excipients- Significance of Substances of Natural Origin as Excipients

S. Selvadurai, S. Divya, A. Geetha, K. Rohini, S. Anbazhagan
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Abstract

As in every field there is a transformation to improve the performance and satisfy the demand of consumer, in pharmaceutical word, need of “Excipient” have been changed from inert and cheap substance which forms bulk of formulation to a material which has potential to be placed in formulation as it accomplished the desirable objective of treatment. The Herbal or natural excipients have a great advantage over their synthetic analogues as these are non-toxic, less expensive and freely available. Due to advances in drug delivery technology, currently, excipients are included in novel dosage forms to fulfill specific functions and in some cases, they directly or indirectly influence the extent and/or rate of drug release and drug absorption. Recent trends towards use of plant based and natural products demand the replacement of synthetic additives with natural ones. Today, the whole world is increasingly interested in natural drugs and excipients, hence natural materials have many advantages over synthetic ones as they are chemically inert, nontoxic, less expensive , biodegradable, improve the shelf life of the product and widely available. This article gives an overview of natural excipients which are used in conventional dosage forms as well as novel drug delivery systems.
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草药辅料。天然来源物质作为辅料的意义
正如在每个领域都有一种转变,以提高性能和满足消费者的需求,在制药领域,对“赋形剂”的需求已经从构成配方主体的惰性和廉价物质转变为一种有潜力的材料,因为它完成了理想的治疗目标。草药或天然赋形剂比它们的合成类似物有很大的优势,因为它们无毒,便宜,而且可以免费获得。由于给药技术的进步,目前,赋形剂被加入到新的剂型中以实现特定的功能,在某些情况下,赋形剂直接或间接地影响药物释放和吸收的程度和/或速度。最近使用植物性和天然产品的趋势要求用天然添加剂代替合成添加剂。今天,全世界对天然药物和赋形剂越来越感兴趣,因此天然材料比合成材料具有许多优点,因为它们具有化学惰性、无毒、便宜、可生物降解、延长产品的保质期和广泛可获得性。这篇文章给出了在传统剂型中使用的天然赋形剂以及新的药物输送系统的概述。
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