Role of fucoidan in stimulating osteoblast cells in alveolar bone loss

Nurlindah Hamrun, Alya Hilda Saifuddin, Alya Khaerunnisa I Day, Hemayu Aditung, Sri Handayani Saharuddin, Megatriani Matandung, Fadilla Ani Saputri, A. Agum Aripratma, A. Muh. Ferdian Alfarabi, Nadya Aura Amalia
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Abstract

Alveolar bone loss is a characteristic of the development of periodontitis; its prevention is a major clinical challenge in the treatment of periodontal disease. Alveolar bone loss can significantly affect a patient's quality of life. In addressing the chal-lenges of recovering alveolar bone loss, fucoidan has attracted attention as a potential material due to its numerous biological activities, one of which is its potential to regulate osteogenic cell function so as to facilitate osteoblast cell proliferation and promote bone mineralization and development. This literature discusses the role of fucoidan, especially in stimulating osteo-blast cells in cases of alveolar bone loss.
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岩藻糖聚糖在牙槽骨丢失中刺激成骨细胞的作用
牙槽骨丢失是牙周炎发展的一个特征;牙周病的预防是牙周病治疗的主要临床挑战。牙槽骨丢失会严重影响患者的生活质量。在解决牙槽骨丢失恢复的挑战时,岩藻糖聚糖由于其众多的生物活性而引起了人们的关注,其中之一是它可能调节成骨细胞的功能,从而促进成骨细胞的增殖,促进骨矿化和发育。本文讨论岩藻糖聚糖的作用,特别是在牙槽骨丢失的情况下刺激成骨细胞。
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