Variation in central corneal thickness in diabetes: A comparative prospective study at a tertiary care hospital

J. Jacob, I. Isaac, Janie Salor, N. Rajendran
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Abstract

Diabetes being the greatest challenge of the century and the fact that it affects almost all of the tissues and organs in the body warrants research into the effects of diabetes on every structure. This study was designed with the aim of finding out any association between diabetes and central corneal thickness and to evaluate the effect of diabetes treatment on central corneal thickness. and non-diabetic A comparative prospective study was conducted to evaluate the effect of on CCT. A total of 84 subjects were studied which included 42 diabetics. After thorough systemic and ocular CCT was measured using ultrasound pachymeter. The study was initiated after obtaining ethical clearance from the ethical clearance committee. The collected data was analysed using SPSS software version 20.0. to bring to light the effects of diabetes on corneal thickness, which in turn might affect even the management of glaucoma. We evaluated a group of diabetics and compared them with matched controls. After conducting this study we arrived at a conclusion that central corneal thickness is increased in diabetics and that control of diabetes doesn’t have a significant effect on central corneal thickness.
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糖尿病患者角膜中央厚度的变化:一家三级医院的比较前瞻性研究
糖尿病是本世纪最大的挑战,它影响人体几乎所有的组织和器官,这一事实值得研究糖尿病对每个结构的影响。本研究旨在探讨糖尿病与角膜中央厚度之间的关系,并评价糖尿病治疗对角膜中央厚度的影响。进行了一项比较前瞻性研究,以评估对CCT的影响。共有84名受试者被研究,其中包括42名糖尿病患者。超声测厚仪测量全身及眼部CCT。该研究是在获得伦理审查委员会的伦理许可后开始的。采用SPSS 20.0软件对收集的数据进行分析。揭示糖尿病对角膜厚度的影响,进而影响青光眼的治疗。我们对一组糖尿病患者进行了评估,并与对照组进行了比较。在进行这项研究后,我们得出结论,糖尿病患者角膜中央厚度增加,糖尿病的控制对角膜中央厚度没有显著影响。
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