Analysis of the Difference in the Prevalence of Metabolic Syndrome According to Sasang Constitution and Cold and Heat Pattern Identification

Ki-Hyun Park, Sang-Hyuk Kim, Siwoo Lee, K. Bae
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Abstract

Objectives: The aim of this study was to investigate the differences in the prevalence of metabolic syndrome (MetS) according to the Sasang constitution (SC) and cold and heat pattern identification (CHPI).Methods: SC, CHPI, MetS, and component data were obtained from 2,561 participants in 26 Korean medical clinics from 2007 to 2013. SC, diagnosed by Korean medicine doctors, was confirmed by positive responses to herbal medicines administered according to that constitution. The CHPI was verified by a questionnaire about thermal sensitivity and drinking habits. The diagnosis criteria for MetS were: 1) waist circumference (WC) ≥90 cm (male) and ≥80 cm (female); 2) triglycerides ≥150 mg/dL; 3) high density lipoprotein cholesterol (HDL) <40 mg/dL (male) and <50 mg/dL (female); 4) blood pressure ≧130/85 mmHg; and 5) fasting blood glucose ≥100 mg/dL. Odds ratios (ORs) and differences in MetS and its components were compared using logistic regression and ANCOVA.Results: The MetS prevalence rates were 54.1%, 22.0%, and 33.3% for Taeeumin (TE), Soeumin (SE), and Soyangin (SY), respectively, and 30.5% and 44.5% for the cold and heat patterns, respectively. ANCOVA for MetS components showed significantly higher WC in TE than in SE or SY, and all components except HDL were higher in the heat pattern group than in the cold pattern group. Logistic regression for MetS prevalence showed a significant association between TE and the heat pattern group (OR=1.653) but not for non-TE and the cold pattern group.Conclusions: Considering SC and CHPI together may be more effective in managing MetS than considering SC alone.
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从沙桑体质和寒热证辨证分析代谢综合征患病率的差异
目的:本研究旨在探讨Sasang体质(SC)和冷热模式识别(CHPI)在代谢综合征(MetS)患病率方面的差异。方法:2007年至2013年,从26家韩国医疗诊所的2561名参与者中获得SC、CHPI、MetS和成分数据。由韩国医生诊断的SC,通过对根据该宪法使用的草药的积极反应得到证实。CHPI通过热敏感性和饮酒习惯问卷进行验证。met的诊断标准为:1)腰围(WC)≥90 cm(男性)、≥80 cm(女性);2)甘油三酯≥150mg /dL;3)高密度脂蛋白胆固醇(HDL) <40 mg/dL(男性)和<50 mg/dL(女性);4)血压≧130/85 mmHg;5)空腹血糖≥100mg /dL。使用logistic回归和ANCOVA比较优势比(ORs)和MetS及其组成部分的差异。结果:Taeeumin (TE)、Soeumin (SE)和Soyangin (SY)的met患病率分别为54.1%、22.0%和33.3%,cold和heat的患病率分别为30.5%和44.5%。met组的ANCOVA结果显示,TE组的WC显著高于SE组和SY组,除HDL外,热模组的WC均高于冷模组。对met患病率的逻辑回归显示TE与热模式组之间存在显著相关性(OR=1.653),但非TE和冷模式组之间无显著相关性。结论:联合使用SC和CHPI可能比单独使用SC更有效地治疗MetS。
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