In-Vitro Antioxidant and Anti-Neoplastic Activity of Leaves Extract of Adina Cardifolia

Shilpi Mishra, Ajay Kumar, Vidhi Jain, Dr. Manmeet Singh Saluja
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Abstract

This study of the antioxidant properties of Adina cardifolia ware successfully investigated using DPPH radical scavenging, nitric oxide radical scavenging, Superoxide anion radical scavenging, total antioxidant activity by ABTS*+ radical scavenging and lipid peroxidation inhibitor assays and compared with the standards. Also the anti-neoplastic activity was study by MTT assay using MCF7 Cell line. Percentage growth inhibition by MTT assay using MCF-7 cell line ware found to be 65.54±1.05 by PEAC extract respectively compared to 83.03±1.0% by standard drug Methotrexate.
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菖蒲叶提取物体外抗氧化及抗肿瘤活性研究
本研究通过DPPH自由基清除、一氧化氮自由基清除、超氧阴离子自由基清除、ABTS*+自由基清除和脂质过氧化抑制剂总抗氧化活性测定,并与标准对照,成功地研究了荻叶草的抗氧化性能。并以MCF7细胞株为实验对象,采用MTT法研究其抗肿瘤活性。用MTT法测定MCF-7细胞株的生长抑制率,PEAC提取物分别为65.54±1.05,而标准药物甲氨蝶呤的抑制率为83.03±1.0%。
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