Shayma L. Abdulhadi, M. Q. Abdulkadir, M. M. Al-Mudhafar
{"title":"The Importance of 2-AminoThiazole Schiff Bases as Antimicrobial and Anticancer Agents","authors":"Shayma L. Abdulhadi, M. Q. Abdulkadir, M. M. Al-Mudhafar","doi":"10.23851/mjs.v31i3.865","DOIUrl":null,"url":null,"abstract":"The pharmacophore 2-aminothiazole has an interesting role in pharmaceutical chemistry as this led to the synthesis of many types of compounds with diverse biological activity. Schiff base derivatives at the same time contribute to drug evolution importantly. In this review, the Schiff base derivatives of 2-aminothiazole formed and some of their metal complexes are being focused on, and the antimicrobial and anticancer activity of them is being illustrated.","PeriodicalId":7515,"journal":{"name":"Al-Mustansiriyah Journal of Sciences","volume":"32 1","pages":"46-64"},"PeriodicalIF":0.0000,"publicationDate":"2020-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Al-Mustansiriyah Journal of Sciences","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.23851/mjs.v31i3.865","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
The pharmacophore 2-aminothiazole has an interesting role in pharmaceutical chemistry as this led to the synthesis of many types of compounds with diverse biological activity. Schiff base derivatives at the same time contribute to drug evolution importantly. In this review, the Schiff base derivatives of 2-aminothiazole formed and some of their metal complexes are being focused on, and the antimicrobial and anticancer activity of them is being illustrated.
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