The Importance of 2-AminoThiazole Schiff Bases as Antimicrobial and Anticancer Agents

Shayma L. Abdulhadi, M. Q. Abdulkadir, M. M. Al-Mudhafar
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Abstract

The pharmacophore 2-aminothiazole has an interesting role in pharmaceutical chemistry as this led to the synthesis of many types of compounds with diverse biological activity. Schiff base derivatives at the same time contribute to drug evolution importantly. In this review, the Schiff base derivatives of 2-aminothiazole formed and some of their metal complexes are being focused on, and the antimicrobial and anticancer activity of them is being illustrated.
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2-氨基噻唑席夫碱作为抗菌和抗癌药物的重要性
药效团2-氨基噻唑在药物化学中有一个有趣的作用,因为它导致了许多具有不同生物活性的化合物的合成。同时,希夫碱衍生物对药物进化也有重要贡献。本文对2-氨基噻唑的希夫碱衍生物及其金属配合物进行了综述,并对其抗菌和抗癌活性进行了阐述。
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