Jing Li, Xiangyi Jiang, Shujing Xu, Q. Cui, Ruikun Du, Dongwei Kang, P. Zhan, L. Rong, Xin Liu
{"title":"Medicinal chemistry strategies in seeking coronavirus inhibitors","authors":"Jing Li, Xiangyi Jiang, Shujing Xu, Q. Cui, Ruikun Du, Dongwei Kang, P. Zhan, L. Rong, Xin Liu","doi":"10.16438/J.0513-4870.2020-0131","DOIUrl":null,"url":null,"abstract":"The epidemic caused by coronavirus poses a serious threat to human health, but there is no specific drug or vaccine for the treatment of this kind of virus infection Herein, this article selects typical case studies in recent years and reviews the medicinal chemistry strategies of anti-SARS-CoV, MERS-CoV and other coronavirus drugs from the perspective of medicinal chemistry, and tries to provide some clues to current drug research against-SARS-CoV-2","PeriodicalId":7092,"journal":{"name":"Acta pharmaceutica Sinica","volume":"67 1","pages":"537-553"},"PeriodicalIF":0.0000,"publicationDate":"2020-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Acta pharmaceutica Sinica","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.16438/J.0513-4870.2020-0131","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Pharmacology, Toxicology and Pharmaceutics","Score":null,"Total":0}
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Abstract
The epidemic caused by coronavirus poses a serious threat to human health, but there is no specific drug or vaccine for the treatment of this kind of virus infection Herein, this article selects typical case studies in recent years and reviews the medicinal chemistry strategies of anti-SARS-CoV, MERS-CoV and other coronavirus drugs from the perspective of medicinal chemistry, and tries to provide some clues to current drug research against-SARS-CoV-2
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