{"title":"Exemestane leads to hormone-associated ascites in female hamsters with experimental metabolic syndrome","authors":"D. Lytkin, A. Zagayko, T. Briukhanova","doi":"10.20517/2572-8180.2019.002","DOIUrl":null,"url":null,"abstract":"Aim: During the study of the aromatase inhibitors effect on metabolic disorders, it was found that exemestane significantly caused ascites. This part of pre-clinical study aimed to investigate the potential dysregulatory effect of exemestan on adrenal synthesis of hormones with miniralocorticoid activity under the conditions of experimental","PeriodicalId":17398,"journal":{"name":"Journal of Unexplored Medical Data","volume":"85 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2019-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Unexplored Medical Data","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.20517/2572-8180.2019.002","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 1
Abstract
Aim: During the study of the aromatase inhibitors effect on metabolic disorders, it was found that exemestane significantly caused ascites. This part of pre-clinical study aimed to investigate the potential dysregulatory effect of exemestan on adrenal synthesis of hormones with miniralocorticoid activity under the conditions of experimental
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