Sensitization to indoor allergens in children with bronchial asthma

K. Chauhan, Shetanshu Srivastava, R. Prasad
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引用次数: 1

Abstract

BACKGROUND: Children with asthma have a high prevalence of environmental allergies. Sensitization to various allergens, especially to indoor allergens is crucial for effective measures for asthma management. Indian data on allergic sensitization in children is scarce, necessitating the need of the study. METHODS: A Cross-sectional study was conducted to determine the indoor allergen sensitization in 100 asthmatic children aged 5 to 15 yrs. They underwent skin prick test for indoor allergen house dust mite cockroach, cat, dog dander, house fly, candida, aspergillus, and mosquito. RESULTS: In the study sensitization to house dust mite was 93%. 39% were sensitized to Candida 36% to cockroach,23% housefly and 22%to dog dander and Aspergillus and 13% to mosquito and cat dander. Allergen sensitivity rate for atleast one allergen was 94% which was significant. Mean No. of allergens for which sensitization was seen is 2.57±1.77. Comorbidities were present in 35% of cases.7% had urticarial and allergic conjunctivitis each. CONCLUSION: Asthmatic children showed high sensitization to indoor allergen and the most common allergen found was house dust mite
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支气管哮喘儿童对室内过敏原的致敏
背景:哮喘患儿环境过敏发生率高。对各种过敏原的致敏,特别是对室内过敏原的致敏对于哮喘管理的有效措施至关重要。印度关于儿童过敏致敏的数据很少,因此有必要进行这项研究。方法:采用横断面研究方法测定100例5 ~ 15岁哮喘儿童室内过敏原致敏情况。对室内过敏原进行皮肤点刺试验,检测室内尘螨、蟑螂、猫、狗皮屑、家蝇、假丝酵母菌、曲霉和蚊子。结果:本研究对室内尘螨的致敏率为93%。对念珠菌敏感的占39%,对蟑螂敏感的占36%,对家蝇敏感的占23%,对狗皮屑和曲霉菌敏感的占22%,对蚊子皮屑和猫皮屑敏感的占13%。对至少一种过敏原的敏感率为94%,这是显著的。意思是没有。致敏率为2.57±1.77。35%的病例存在合并症。7%的患者有荨麻疹和过敏性结膜炎。结论:哮喘患儿对室内过敏原有较高的致敏性,最常见的过敏原是屋尘螨
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