Application of propensity score method to analyze the effect of Maixuekang capsule on the treatment outcome of coronary heart disease

Ren-bo Chen, Guo-zhong Gai, Wen-li Zhang, Yan Zhuang, Yanming Xie
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Abstract

Objective To analyze the effect of Maixuekang Capsule on the treatment outcome of coronary heart disease (CHD) by propensity score. Methods Based on the electronic medical record database of 22 large-scale tertiary hospitals nationwide, this study matched the coronary heart disease patients using and not using Maixuekang capsule according to a certain standard (1∶1). After matching, there were 2 464 cases in the patients group (group A) and the patients group (group B). In the database, the recombination of " recovery" and " improvement" is defined as effective treatment, and " invalid" , " death" and " other" are combined as ineffective treatment population. The effectiveness of the two groups after the re combination is compared by propensity score. Results The results of χ2 test showed that the difference between the two groups was statistically significant (P 0, and there was statistical significance (P<0.01). Conclusions The therapeutic effect of Maixuekang capsule on coronary heart disease is higher than that of patients without the drug. Key words: Propensity score; Maixuekang capsule; Coronary disease; Electronic health records
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应用倾向评分法分析脉血康胶囊对冠心病治疗效果的影响
目的应用倾向评分法分析脉血康胶囊对冠心病(CHD)治疗效果的影响。方法以全国22家大型三级医院的电子病历数据库为基础,按照一定的标准(1∶1)对使用脉血康胶囊和未使用脉血康胶囊的冠心病患者进行匹配。经匹配后,患者组(A组)和患者组(B组)共2 464例。在数据库中,将“恢复”和“改善”合并定义为有效治疗,将“无效”、“死亡”和“其他”合并定义为无效治疗人群。采用倾向评分法比较两组合并后的疗效。结果χ2检验结果显示,两组间差异有统计学意义(P<0.01),差异有统计学意义(P<0.01)。结论脉血康胶囊治疗冠心病的疗效高于未用药组。关键词:倾向评分;Maixuekang胶囊;冠状动脉疾病;电子健康记录
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中国医师杂志
中国医师杂志 Medicine-Medicine (all)
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0.10
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20937
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