A cross-sectional study on the compliance to antihypertensive drugs in a rural area

S. Pandian, M Vijaykarthikeyan, R. Umadevi
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Abstract

Background: The burden of the non-communicable diseases (NCDs) is increasing over the years. Worldwide, the leading cause of morbidity and mortality has been due to NCDs. Although NCDs are multifactorial, hypertension plays a major role as a risk factor. Lack of treatment adherence can lead to negative health consequences. Objectives: The objectives of the study were as follows: (1) To assess patients’ compliance to antihypertensive drugs; (2) to evaluate association between treatment compliance and sociodemographic determinants; and (3) to find out the factors responsible for non-adherence. Materials and Methods: This study was carried among 350 hypertensive patients in the rural field practice area of a medical college using simple random sampling method. The study population consists of hypertensive patients belonging to 20–60 years of age. A pretested structured questionnaire containing Morisky’s scale was used to assess patient’s adherence. Data analysis was done using SPSS (Version 22). Results: Nearly 53.7% of the study participants were female. The prevalence of treatment compliance was estimated to be 24.6%. Statistically significant association was observed between age, education, and socioeconomic status with adherence to hypertensive medications (P < 0.05). Many reasons were identified for non-adherence and they include cost of treatment (21.4 %), side effects (27.5%), alternative treatment (16%), lack of knowledge (32.8%), and multiple drugs (25%). Conclusion: The prevalence of 23.6% of patient’s being adherent to hypertensive medications was observed among the study population. It is necessary to strengthen treatment adherence by various health education campaigns and implementing various health programs.
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农村地区降压药依从性的横断面研究
背景:近年来,非传染性疾病(NCDs)的负担不断增加。在世界范围内,发病率和死亡率的主要原因是非传染性疾病。虽然非传染性疾病是多因素的,但高血压作为一个危险因素起着主要作用。缺乏治疗依从性可导致负面的健康后果。目的:本研究的目的如下:(1)评估患者对降压药物的依从性;(2)评估治疗依从性与社会人口统计学决定因素之间的关系;(3)找出导致不依从的因素。材料与方法:采用简单随机抽样的方法对某医学院农村实习区350例高血压患者进行研究。研究人群为20 - 60岁的高血压患者。采用预先测试的结构化问卷(包含Morisky量表)来评估患者的依从性。使用SPSS (Version 22)进行数据分析。结果:近53.7%的研究参与者为女性。治疗依从率估计为24.6%。年龄、受教育程度和社会经济地位与高血压药物依从性有统计学意义(P < 0.05)。不坚持治疗的原因有很多,包括治疗费用(21.4%)、副作用(27.5%)、替代治疗(16%)、缺乏相关知识(32.8%)和多种药物(25%)。结论:研究人群高血压药物依从率为23.6%。有必要通过各种健康教育活动和实施各种健康方案来加强治疗依从性。
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