Effects of onabotulinumtoxin A in patients concurrently diagnosed with chronic migraine encephalalgia and temporomandibular disorders: A retrospective case series.
Andrew J Gross, John W Hudson, Catalina Matias, Brady J Jones
{"title":"Effects of onabotulinumtoxin A in patients concurrently diagnosed with chronic migraine encephalalgia and temporomandibular disorders: A retrospective case series.","authors":"Andrew J Gross, John W Hudson, Catalina Matias, Brady J Jones","doi":"10.1080/08869634.2022.2045114","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>Chronic migraine encephalalgia (CME) with concomitant temporomandibular disorder (TMD) is a serious illness with limited effective treatment options. This study explores the effectiveness of onabotulinumtoxinA (BtxA) as an adjunct therapeutic to TMJ arthroscopy in the relief of CME.</p><p><strong>Methods: </strong>A retrospective cohort study of patients receiving TMJ arthroscopy, with or without BtxA injections for CME, was conducted. Variables assessed include pain using a visual analog scale (VAS), maximal incisal opening (MIO), muscle soreness, and headache frequency and duration.</p><p><strong>Results: </strong>Sixty patients (44 BtxA, 16 Control), consisting of 56 (93.3%) females, met inclusion criteria. A significant reduction in pain is reported with patients receiving BtxA (<i>p</i> < 0.0001) on VAS as compared to Control group. BtxA treatment also significantly reduced headache frequency and duration (<i>p</i> < 0.05).</p><p><strong>Conclusion: </strong>These results support the use of adjunctive BtxA treatment with arthroscopy for the treatment of CME in the context of TMD.</p>","PeriodicalId":20069,"journal":{"name":"Physical review letters","volume":"35 1","pages":"688-698"},"PeriodicalIF":8.1000,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Physical review letters","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1080/08869634.2022.2045114","RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2022/3/14 0:00:00","PubModel":"Epub","JCR":"Q1","JCRName":"PHYSICS, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 0
Abstract
Objective: Chronic migraine encephalalgia (CME) with concomitant temporomandibular disorder (TMD) is a serious illness with limited effective treatment options. This study explores the effectiveness of onabotulinumtoxinA (BtxA) as an adjunct therapeutic to TMJ arthroscopy in the relief of CME.
Methods: A retrospective cohort study of patients receiving TMJ arthroscopy, with or without BtxA injections for CME, was conducted. Variables assessed include pain using a visual analog scale (VAS), maximal incisal opening (MIO), muscle soreness, and headache frequency and duration.
Results: Sixty patients (44 BtxA, 16 Control), consisting of 56 (93.3%) females, met inclusion criteria. A significant reduction in pain is reported with patients receiving BtxA (p < 0.0001) on VAS as compared to Control group. BtxA treatment also significantly reduced headache frequency and duration (p < 0.05).
Conclusion: These results support the use of adjunctive BtxA treatment with arthroscopy for the treatment of CME in the context of TMD.
期刊介绍：
Physical review letters(PRL)covers the full range of applied, fundamental, and interdisciplinary physics research topics:
General physics, including statistical and quantum mechanics and quantum information
Gravitation, astrophysics, and cosmology
Elementary particles and fields
Nuclear physics
Atomic, molecular, and optical physics
Nonlinear dynamics, fluid dynamics, and classical optics
Plasma and beam physics
Condensed matter and materials physics
Polymers, soft matter, biological, climate and interdisciplinary physics, including networks
京公网安备 11010802042870号
京ICP备2023020795号-1
分享
求助内容：
应助结果提醒方式：
扫码关注我们
