Antimicrobial Metabolites Producing Soil Microorganisms: An update

A. Pandey, N. Chandra, A. Srivastava, Dheerendra Kumar, Sunil Kumar
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引用次数: 1

Abstract

Secondary metabolites are defined as small organic molecules produced by organisms which are not essential for their growth, development and reproduction. These compounds work as antimicrobial, antitumor and/or antiviral against pathogenic microorganisms. Actinomycetes are one of the most prominent species among various groups of microorganisms, which have the capacity of producing secondary metabolites. It has been reported that more than 70% of the antibiotics have been obtained from members of the Actinomycetes family till date. Hence it has been suggested that a large number of Actinomycetes may still be unknown with a potential to produce antibiotics. In present scenario, the emergence of multidrug resistant bacteria has forced the scientific community for the development of novel antibiotics for treatment of various human and animal diseases with such type of bacterial infections. This review has been carried out to update the scientific communities regarding the developments on antibiotics producing soil microorganisms.
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产生土壤微生物的抗菌代谢物:最新进展
次生代谢物被定义为生物体产生的对其生长、发育和繁殖不是必需的小有机分子。这些化合物对病原微生物具有抗菌、抗肿瘤和/或抗病毒作用。放线菌是各种微生物群中最突出的一种,具有产生次生代谢产物的能力。据报道,到目前为止,超过70%的抗生素是从放线菌家族的成员中获得的。因此,有人提出,大量放线菌可能仍是未知的,具有生产抗生素的潜力。在目前的情况下,耐多药细菌的出现迫使科学界开发新的抗生素来治疗由这类细菌感染引起的各种人类和动物疾病。本文综述了产生抗生素的土壤微生物的最新研究进展。
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