M. Boulakia, M. Fernández, Jean-Frédéric Gerbeau, N. Zemzemi
{"title":"A Coupled System of PDEs and ODEs Arising in Electrocardiograms Modeling","authors":"M. Boulakia, M. Fernández, Jean-Frédéric Gerbeau, N. Zemzemi","doi":"10.1093/AMRX/ABN002","DOIUrl":null,"url":null,"abstract":"We study the well-posedness of a coupled system of PDEs and ODEs arising in the numerical simulation of electrocardiograms. It consists of a system of degenerate reaction-diffusion equations, the so-called bidomain equations, governing the electrical activity of the heart, and a diffusion equation governing the potential in the surrounding tissues. Global existence of weak solutions is proved for an abstract class of ionic models including Mitchell-Schaeffer, FitzHugh-Nagumo, Aliev-Panfilov and MacCulloch. Uniqueness is proved in the case of the FitzHugh-Nagumo ionic model. The proof is based on a regularisation argument with a Faedo-Galerkin/compactness procedure.","PeriodicalId":89656,"journal":{"name":"Applied mathematics research express : AMRX","volume":"75 1","pages":"24"},"PeriodicalIF":0.0000,"publicationDate":"2010-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"60","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Applied mathematics research express : AMRX","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1093/AMRX/ABN002","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 60
Abstract
We study the well-posedness of a coupled system of PDEs and ODEs arising in the numerical simulation of electrocardiograms. It consists of a system of degenerate reaction-diffusion equations, the so-called bidomain equations, governing the electrical activity of the heart, and a diffusion equation governing the potential in the surrounding tissues. Global existence of weak solutions is proved for an abstract class of ionic models including Mitchell-Schaeffer, FitzHugh-Nagumo, Aliev-Panfilov and MacCulloch. Uniqueness is proved in the case of the FitzHugh-Nagumo ionic model. The proof is based on a regularisation argument with a Faedo-Galerkin/compactness procedure.