A Coupled System of PDEs and ODEs Arising in Electrocardiograms Modeling

M. Boulakia, M. Fernández, Jean-Frédéric Gerbeau, N. Zemzemi
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引用次数: 60

Abstract

We study the well-posedness of a coupled system of PDEs and ODEs arising in the numerical simulation of electrocardiograms. It consists of a system of degenerate reaction-diffusion equations, the so-called bidomain equations, governing the electrical activity of the heart, and a diffusion equation governing the potential in the surrounding tissues. Global existence of weak solutions is proved for an abstract class of ionic models including Mitchell-Schaeffer, FitzHugh-Nagumo, Aliev-Panfilov and MacCulloch. Uniqueness is proved in the case of the FitzHugh-Nagumo ionic model. The proof is based on a regularisation argument with a Faedo-Galerkin/compactness procedure.
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心电图建模中的偏微分方程和偏微分方程耦合系统
我们研究了在心电图数值模拟中出现的偏微分方程和偏微分方程耦合系统的适定性。它包括一个简并反应扩散方程系统,即所谓的双域方程,控制心脏的电活动,以及一个控制周围组织电位的扩散方程。证明了一类离子模型(包括Mitchell-Schaeffer、FitzHugh-Nagumo、Aliev-Panfilov和MacCulloch)弱解的整体存在性。证明了FitzHugh-Nagumo离子模型的唯一性。证明是基于正则化论证与Faedo-Galerkin/紧性过程。
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