{"title":"Biofabricated Silver Nanoparticles Synergistically Activate Amphotericin B Against Mature Biofilm Forms of","authors":"S. Halbandge, Supriya P. Mortale, S. Karuppayil","doi":"10.2174/1875933501704010001","DOIUrl":null,"url":null,"abstract":"Received: April 27, 2017 Revised: July 27, 2017 Accepted: August 10, 2017 Abstract: Background: Biofilm formation by Candida albicans is a significant clinical challenge. Fungal biofilms are resistant to most of the currently available antifungal agents. Amphotericin-B (AmB) is an antifungal agent used for the treatment of systematic fungal infections but it is well known for its toxicities and side-effects. Novel approaches are needed to treat these infections that can reduce its toxicities.","PeriodicalId":22993,"journal":{"name":"The Open Nanomedicine Journal","volume":"8 1","pages":"1-16"},"PeriodicalIF":0.0000,"publicationDate":"2017-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"12","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"The Open Nanomedicine Journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2174/1875933501704010001","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 12
Abstract
Received: April 27, 2017 Revised: July 27, 2017 Accepted: August 10, 2017 Abstract: Background: Biofilm formation by Candida albicans is a significant clinical challenge. Fungal biofilms are resistant to most of the currently available antifungal agents. Amphotericin-B (AmB) is an antifungal agent used for the treatment of systematic fungal infections but it is well known for its toxicities and side-effects. Novel approaches are needed to treat these infections that can reduce its toxicities.
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