Cryptosporidiosis in HIV-seronegative patients: A case series

Drishti Sagar, H. Kaur
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Abstract

Enteric infections by are a frequent cause of diarrhea among immunocompromised and HIV infected patients but there are limited reports of their occurrence in immunocompetent patients. Cryptosporidiosis is a faeco-orally transmitted protozoan infection and is one of the leading causes of chronic parasitic diarrhea. Here we report a case series of cryptosporidiosis from three different patients where two patients are immunocompetent and one is a post renal transplant case. All the patients came with watery diarrhea for which stool samples were collected and examined by modified Ziehl Neelsen acid fast staining (Kinyoun’s method). On microscopic examination of smear, multiple, pink, round to oval acid fast oocysts of 4-6µm diameter were seen against a blue background morphologically resembling . Early diagnosis and prompt initiation of antiparasitic drugs aids in timely treatment and prevention of disseminated cryptosporidiosis.
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hiv血清阴性患者的隐孢子虫病:一个病例系列
肠道感染是免疫功能低下和HIV感染患者腹泻的常见原因,但在免疫功能正常的患者中发生的报道有限。隐孢子虫病是一种粪口传播的原生动物感染,是慢性寄生虫性腹泻的主要原因之一。在这里,我们报告了三个不同患者的隐孢子虫病病例系列,其中两个患者免疫功能正常,一个是肾移植后病例。所有患者均为水样腹泻,收集粪便标本,采用改良的Ziehl - Neelsen耐酸染色(Kinyoun法)进行检查。涂片镜检可见,在蓝色背景下,可见多个、粉红色、圆形至椭圆形的抗酸卵囊,直径4-6µm,形态相似。早期诊断和及时使用抗寄生虫药物有助于及时治疗和预防播散性隐孢子虫病。
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