Assessment of Antifungal Properties of the Exudate Gel from the Stem of Caralluma retrospiciens Against Clinical Isolate of Candida albicans

S. S. Moni, S. Menachery, M. E. Elmobark, M. F. Alam, Gassem Gohal, K. Abdelsalam, Soha Taymour, V. K. Basode, D. Banji
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Abstract

The desert plant C. retrospiciens (Ehrenb.) is an inhabitant of the southern region of Kingdom of Saudi Arabia (KSA). The stem of C. retrospiciens produces a gel which is often applied by local people to cure wounds. This study was aimed at determination of the antifungal effect of the exudate gel (EG) against Candida albicans (C. albicans). The antifungal activity of EG was measured using agar well diffusion method. Results showed excellent antifungal activity of the exudate gel. The spectrum of antifungal activity of EG against C. albicans was almost equivalent to that of standard amphotericin B, with statistical insignificance (p < 0.05).
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反花苜蓿茎渗出凝胶对白色念珠菌临床分离株的抑菌性能评价
沙漠植物C. retrospiciens (Ehrenb.)是沙特阿拉伯王国(KSA)南部地区的一种植物。这种植物的茎会产生一种凝胶,当地人经常用这种凝胶来治疗伤口。本研究旨在测定渗出凝胶(EG)对白色念珠菌(C. albicans)的抗真菌作用。用琼脂孔扩散法测定EG的抑菌活性。结果表明,该渗出液具有良好的抗真菌活性。EG对白色念珠菌的抑菌活性谱与标准两性霉素B的抑菌活性谱基本相当,差异无统计学意义(p < 0.05)。
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