Pub Date : 2024-05-10DOI: 10.36348/sjmps.2024.v10i05.002
Hamid, M. A, Sen, S. L, Moniruzzaman, S, Mukit, S. M. A, Sultana, S. N, Biswas, G
Introduction: Burn injuries remain a significant public health issue, especially in low- and middle-income countries where comprehensive data is scarce. This study provides a detailed analysis of burn injuries in Northern Bangladesh, focusing on epidemiological characteristics and factors influencing burn severity and incidents. Methods: This retrospective study analyzed 477 cases of acute, unintentional burns recorded between January 2022 and December 2022 at the Rangpur Medical College Hospital's Burn and Plastic Surgery unit. Data on demographics, burn types, etiology, and severity were collected from hospital registers. Statistical analysis, including chi-square tests and logistic regression, was used to identify predictors of burn severity. Result: Of the 477 documented cases, females represented 62.05% (296 cases) and males 37.95% (181 cases). Flame burns predominated, comprising 70% of incidents, significantly impacting females engaged in cooking activities. The data revealed a distinct seasonal trend with a significant peak in January, where 40% (191 cases) of annual burn incidents occurred due to campfire exposure. The analysis further demonstrated that burns covering more than 30% of total body surface area (TBSA) were significantly associated with higher morbidity and mortality, with third-degree burns occurring in 92.9% of females compared to 55.8% of males. Logistic regression identified age (OR = 1.28, CI [1.13-2.71]), gender (OR = 1.75, CI [1.11-1.47]), and the cause of ignition (OR = 0.56, CI [0.41-0.76]) as significant predictors of burn severity. Conclusion: The findings emphasize the need for targeted interventions to address the high incidence of burns among young to middle-aged women, particularly through safer cooking practices and awareness campaigns. Additionally, public health strategies should consider seasonal risks and promote safer heating methods during colder months. This study underlines critical areas for intervention and highlights the importance of culturally tailored public health strategies to reduce burn injuries in Northern Bangladesh.
{"title":"An Analysis of Hospitalized Burn Injuries in a Burn Care Unit of Northern Bangladesh","authors":"Hamid, M. A, Sen, S. L, Moniruzzaman, S, Mukit, S. M. A, Sultana, S. N, Biswas, G","doi":"10.36348/sjmps.2024.v10i05.002","DOIUrl":"https://doi.org/10.36348/sjmps.2024.v10i05.002","url":null,"abstract":"Introduction: Burn injuries remain a significant public health issue, especially in low- and middle-income countries where comprehensive data is scarce. This study provides a detailed analysis of burn injuries in Northern Bangladesh, focusing on epidemiological characteristics and factors influencing burn severity and incidents. Methods: This retrospective study analyzed 477 cases of acute, unintentional burns recorded between January 2022 and December 2022 at the Rangpur Medical College Hospital's Burn and Plastic Surgery unit. Data on demographics, burn types, etiology, and severity were collected from hospital registers. Statistical analysis, including chi-square tests and logistic regression, was used to identify predictors of burn severity. Result: Of the 477 documented cases, females represented 62.05% (296 cases) and males 37.95% (181 cases). Flame burns predominated, comprising 70% of incidents, significantly impacting females engaged in cooking activities. The data revealed a distinct seasonal trend with a significant peak in January, where 40% (191 cases) of annual burn incidents occurred due to campfire exposure. The analysis further demonstrated that burns covering more than 30% of total body surface area (TBSA) were significantly associated with higher morbidity and mortality, with third-degree burns occurring in 92.9% of females compared to 55.8% of males. Logistic regression identified age (OR = 1.28, CI [1.13-2.71]), gender (OR = 1.75, CI [1.11-1.47]), and the cause of ignition (OR = 0.56, CI [0.41-0.76]) as significant predictors of burn severity. Conclusion: The findings emphasize the need for targeted interventions to address the high incidence of burns among young to middle-aged women, particularly through safer cooking practices and awareness campaigns. Additionally, public health strategies should consider seasonal risks and promote safer heating methods during colder months. This study underlines critical areas for intervention and highlights the importance of culturally tailored public health strategies to reduce burn injuries in Northern Bangladesh.","PeriodicalId":21367,"journal":{"name":"Saudi Journal of Medical and Pharmaceutical Sciences","volume":" 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140992645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-10DOI: 10.36348/sjmps.2024.v10i05.003
DR. Mugni Sunny, DR. Kamrunnahar
Background: Postpartum cardiomyopathy is an unusual type of heart failure during pregnancy that can result in significant maternal mortality in underdeveloped nations. The risk factors and in-hospital outcomes of this illness are still poorly known. Objective: To find out the risk factors and postpartum cardiomyopathy in hospital outcomes in a tertiary level hospital in Bangladesh. Materials and Methods: This descriptive study was conducted from January 1st 2022 to Dec 30th 2022 in the Department of Cardiology, Northeast Medical College, Sylhet, Bangladesh. PPCM was diagnosed as left ventricular ejection fraction (LVEF) ≤ 45% toward the end of pregnancy or within 05 months after delivery by standard Echocardiographic evaluation. In this study 77 cases of PPCM enrolled, excluding other causes of heart failure. Results: The mean age was found 27.0±5.83 years. Majority (45.45%) patients were diabetes mellitus followed by 26 (33.7%) hypertension, 33 (42.86%) obesity, 29 (37.66%) anemia, 16 (20.78%) pre-eclampsia and 14 (18.18%) dyslipidemia. Total 24(31.17%) were dead, 4(5.19%) were complete recovery, 12(15.58%) were partial recovery and 37(48.05%) were still suffering from heart failure. Conclusion: Diabetes, hypertension, obesity, anemia, pre-eclampsia, and dyslipidemia were all found as risk factors for postpartum cardiomyopathy in this study.
{"title":"Examination of Risk Factors and Postpartum Cardiomyopathy in Hospital Outcomes in a Tertiary Level Hospital in Bangladesh","authors":"DR. Mugni Sunny, DR. Kamrunnahar","doi":"10.36348/sjmps.2024.v10i05.003","DOIUrl":"https://doi.org/10.36348/sjmps.2024.v10i05.003","url":null,"abstract":"Background: Postpartum cardiomyopathy is an unusual type of heart failure during pregnancy that can result in significant maternal mortality in underdeveloped nations. The risk factors and in-hospital outcomes of this illness are still poorly known. Objective: To find out the risk factors and postpartum cardiomyopathy in hospital outcomes in a tertiary level hospital in Bangladesh. Materials and Methods: This descriptive study was conducted from January 1st 2022 to Dec 30th 2022 in the Department of Cardiology, Northeast Medical College, Sylhet, Bangladesh. PPCM was diagnosed as left ventricular ejection fraction (LVEF) ≤ 45% toward the end of pregnancy or within 05 months after delivery by standard Echocardiographic evaluation. In this study 77 cases of PPCM enrolled, excluding other causes of heart failure. Results: The mean age was found 27.0±5.83 years. Majority (45.45%) patients were diabetes mellitus followed by 26 (33.7%) hypertension, 33 (42.86%) obesity, 29 (37.66%) anemia, 16 (20.78%) pre-eclampsia and 14 (18.18%) dyslipidemia. Total 24(31.17%) were dead, 4(5.19%) were complete recovery, 12(15.58%) were partial recovery and 37(48.05%) were still suffering from heart failure. Conclusion: Diabetes, hypertension, obesity, anemia, pre-eclampsia, and dyslipidemia were all found as risk factors for postpartum cardiomyopathy in this study.","PeriodicalId":21367,"journal":{"name":"Saudi Journal of Medical and Pharmaceutical Sciences","volume":" 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140992084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-06DOI: 10.36348/sjmps.2024.v10i05.001
K. M, S. D, B. H, T. M, K. I, T. Y, H. M, B. K, Koné D, K. A, D. M, Touré D, Diarra A S, D. F, D. O, Traoré Fd
The main cause of chronic HBsAg carriage is mother-to-child transmission. The aim of the study was to determine the epidemiological, clinical and biological aspects of mother-to-child transmission of the hepatitis B virus in newborns of HBsAg-positive mothers. Methodology: This was a descriptive cross-sectional study which took place from 1 March 2020 to 30 June 2021 at the CSREF in Commune V. Sampling was exhaustive, and all newborns whose mothers were carriers of hepatitis B were included in the study. Results: One hundred and twenty newborns out of 3197 referred from the maternity unit, representing a frequency of 3.7% of hepatitis B in pregnant women. Eighty newborns were included. The other 40 were not included because the mothers refused. Among the mothers, 11/80 tested positive for HBeAg and anti-HBs, with 2 positive results (18.18%). Twelve pregnant women had viral load tests, with two positive results (16.66%). Six of the 80 pregnant women had received tenofovir during pregnancy (7.5%), and all the newborns had negative HBsAg results at 4 months of age. Conclusion : Low realization of viral markers of hepatitis B and treatment during pregnancy.
{"title":"Transmission of Hepatitis B in Newborn Mothers with Positive Hbs in the Csref of Commune V of the District of Bamako","authors":"K. M, S. D, B. H, T. M, K. I, T. Y, H. M, B. K, Koné D, K. A, D. M, Touré D, Diarra A S, D. F, D. O, Traoré Fd","doi":"10.36348/sjmps.2024.v10i05.001","DOIUrl":"https://doi.org/10.36348/sjmps.2024.v10i05.001","url":null,"abstract":"The main cause of chronic HBsAg carriage is mother-to-child transmission. The aim of the study was to determine the epidemiological, clinical and biological aspects of mother-to-child transmission of the hepatitis B virus in newborns of HBsAg-positive mothers. Methodology: This was a descriptive cross-sectional study which took place from 1 March 2020 to 30 June 2021 at the CSREF in Commune V. Sampling was exhaustive, and all newborns whose mothers were carriers of hepatitis B were included in the study. Results: One hundred and twenty newborns out of 3197 referred from the maternity unit, representing a frequency of 3.7% of hepatitis B in pregnant women. Eighty newborns were included. The other 40 were not included because the mothers refused. Among the mothers, 11/80 tested positive for HBeAg and anti-HBs, with 2 positive results (18.18%). Twelve pregnant women had viral load tests, with two positive results (16.66%). Six of the 80 pregnant women had received tenofovir during pregnancy (7.5%), and all the newborns had negative HBsAg results at 4 months of age. Conclusion : Low realization of viral markers of hepatitis B and treatment during pregnancy.","PeriodicalId":21367,"journal":{"name":"Saudi Journal of Medical and Pharmaceutical Sciences","volume":" 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141129539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-16DOI: 10.36348/sjmps.2024.v10i04.006
Sheikh Shohag, Shomaya Akhter, Md Abdul Alim, Md. Farhad Munshi, Mohammad Nazir Hossain
Diabetes mellitus (DM) is a global health issue due to its prevalence and catastrophic health effects. Synthetic hypoglycemic agents can treat diabetes, but they have side effects. Therefore, natural remedies for diabetes are now gaining popularity. Marine benthic algae are rich in phytochemicals and other bioactive compounds. Inhibition of carbohydrate hydrolyzing enzymes in-vitro and lower blood glucose levels in-vivo during fasting and postprandial testing imply seaweed extracts and their bioactive ingredients may treat diabetes. This study investigated the phytochemical properties of Asparagopsis taxiformis from the southern part of St. Martin Island in Bangladesh and examined the anti-diabetic activity of its 50% ethanolic extracts in-vitro and in-vivo. After establishing traditional phytochemical presence, total phenolic and flavonoid content was estimated, and an in-vitro alpha-amylase inhibitory activity test was performed. In-vitro anti-diabetic investigation shows that 50% ethanolic extract of Asparagopsis taxiformis reduces diabetes less than acarbose. In-vivo anti-diabetic tests also showed similar results compared to the control group when their blood glucose level was measured. After 14 days of treatment with the 50% ethanolic extract of Asparagopsis taxiformis, the treated group of mice didn’t show any considerable lowering activity when their body weight, lipid profile, kidney function, and liver function (SGPT, SGOT) were compared to the control group. Though Asparagopsis taxiformis has manifold benefits, 50% ethanolic extract of this alga didn’t show any antidiabetic properties suggesting more studies in different solvents are required to evaluate the antidiabetic properties.
{"title":"Phytochemical Profiling and Investigating of Anti-Diabetic Properties of Asparagopsis taxiformis Collected from the Bay of Bengal Bangladesh","authors":"Sheikh Shohag, Shomaya Akhter, Md Abdul Alim, Md. Farhad Munshi, Mohammad Nazir Hossain","doi":"10.36348/sjmps.2024.v10i04.006","DOIUrl":"https://doi.org/10.36348/sjmps.2024.v10i04.006","url":null,"abstract":"Diabetes mellitus (DM) is a global health issue due to its prevalence and catastrophic health effects. Synthetic hypoglycemic agents can treat diabetes, but they have side effects. Therefore, natural remedies for diabetes are now gaining popularity. Marine benthic algae are rich in phytochemicals and other bioactive compounds. Inhibition of carbohydrate hydrolyzing enzymes in-vitro and lower blood glucose levels in-vivo during fasting and postprandial testing imply seaweed extracts and their bioactive ingredients may treat diabetes. This study investigated the phytochemical properties of Asparagopsis taxiformis from the southern part of St. Martin Island in Bangladesh and examined the anti-diabetic activity of its 50% ethanolic extracts in-vitro and in-vivo. After establishing traditional phytochemical presence, total phenolic and flavonoid content was estimated, and an in-vitro alpha-amylase inhibitory activity test was performed. In-vitro anti-diabetic investigation shows that 50% ethanolic extract of Asparagopsis taxiformis reduces diabetes less than acarbose. In-vivo anti-diabetic tests also showed similar results compared to the control group when their blood glucose level was measured. After 14 days of treatment with the 50% ethanolic extract of Asparagopsis taxiformis, the treated group of mice didn’t show any considerable lowering activity when their body weight, lipid profile, kidney function, and liver function (SGPT, SGOT) were compared to the control group. Though Asparagopsis taxiformis has manifold benefits, 50% ethanolic extract of this alga didn’t show any antidiabetic properties suggesting more studies in different solvents are required to evaluate the antidiabetic properties.","PeriodicalId":21367,"journal":{"name":"Saudi Journal of Medical and Pharmaceutical Sciences","volume":"314 3‐4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140698128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-05DOI: 10.36348/sjmps.2024.v10i04.004
H. E. Bacha, M. Konso, I. E. Hamraoui, Y. Smiti, N. Benzzoubeir, I. Errabih
Chronic hepatopathies are cosmopolitan disorders, the most common of which are chronic hepatitis and cirrhosis. Cirrhosis is a pathology of diverse etiologies characterized by diffuse disorganization of the normal hepatic structure due to hepatocyte destruction, with the appearance of regenerative nodules surrounded by fibrosis compressing the hepatic vascularization and causing portal hypertension. We report the case of a patient hospitalized in intensive care for decompensation of chronic hepathopathy during her 4th pregnancy, and we will describe the various consequences of pregnancy on this type of hepathopathy and vice versa via a detailed review of the literature.
{"title":"Decompensation of Chronic Liver Disease during Pregnancy, a Case Report","authors":"H. E. Bacha, M. Konso, I. E. Hamraoui, Y. Smiti, N. Benzzoubeir, I. Errabih","doi":"10.36348/sjmps.2024.v10i04.004","DOIUrl":"https://doi.org/10.36348/sjmps.2024.v10i04.004","url":null,"abstract":"Chronic hepatopathies are cosmopolitan disorders, the most common of which are chronic hepatitis and cirrhosis. Cirrhosis is a pathology of diverse etiologies characterized by diffuse disorganization of the normal hepatic structure due to hepatocyte destruction, with the appearance of regenerative nodules surrounded by fibrosis compressing the hepatic vascularization and causing portal hypertension. We report the case of a patient hospitalized in intensive care for decompensation of chronic hepathopathy during her 4th pregnancy, and we will describe the various consequences of pregnancy on this type of hepathopathy and vice versa via a detailed review of the literature.","PeriodicalId":21367,"journal":{"name":"Saudi Journal of Medical and Pharmaceutical Sciences","volume":"30 16","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140737847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-05DOI: 10.36348/sjmps.2024.v10i04.003
Sulaiman Turki Arfaj Alanazi, Ahmed Tabaan Alenezi
Background: Gallbladder diverticula have the appearance of hernia-like protrusions of the gallbladder wall. This disorder may not be diagnosed until surgically resected because it has no clinical significance unless there are associated diseases. Gallbladder pseudodiverticula have an acquired cause, multiple fundal lesions, an association with gallstones, internal saccular lesions without external hernia-like protrusions, and little to no smooth muscle in the gallbladder wall. Case Presentation: A 15-year-old boy in Saudi Arabia presented with right hypochondrial pain and dyspepsia. Imaging revealed innumerable gallstones in a distended gallbladder, indicative of chronic calculous cholecystitis. Elevated liver enzymes and coagulation abnormalities initially postponed surgery, but subsequent improvement allowed for laparoscopic cholecystectomy. Histopathological examination confirmed chronic calcular cholecystitis without malignancy. Conclusion: This case underscores the importance of recognizing and managing chronic calculous cholecystitis in adolescents promptly especially if associated with complication as pseudodiverticula. Successful treatment with laparoscopic cholecystectomy resulted in a positive outcome for the patient. Further research and case studies in this age group can enhance our understanding of the disease and optimize management strategies.
{"title":"Gallbladder Diverticula in Chronic Calculous Cholecystitis 15-Year-Old Boy: Case Report","authors":"Sulaiman Turki Arfaj Alanazi, Ahmed Tabaan Alenezi","doi":"10.36348/sjmps.2024.v10i04.003","DOIUrl":"https://doi.org/10.36348/sjmps.2024.v10i04.003","url":null,"abstract":"Background: Gallbladder diverticula have the appearance of hernia-like protrusions of the gallbladder wall. This disorder may not be diagnosed until surgically resected because it has no clinical significance unless there are associated diseases. Gallbladder pseudodiverticula have an acquired cause, multiple fundal lesions, an association with gallstones, internal saccular lesions without external hernia-like protrusions, and little to no smooth muscle in the gallbladder wall. Case Presentation: A 15-year-old boy in Saudi Arabia presented with right hypochondrial pain and dyspepsia. Imaging revealed innumerable gallstones in a distended gallbladder, indicative of chronic calculous cholecystitis. Elevated liver enzymes and coagulation abnormalities initially postponed surgery, but subsequent improvement allowed for laparoscopic cholecystectomy. Histopathological examination confirmed chronic calcular cholecystitis without malignancy. Conclusion: This case underscores the importance of recognizing and managing chronic calculous cholecystitis in adolescents promptly especially if associated with complication as pseudodiverticula. Successful treatment with laparoscopic cholecystectomy resulted in a positive outcome for the patient. Further research and case studies in this age group can enhance our understanding of the disease and optimize management strategies.","PeriodicalId":21367,"journal":{"name":"Saudi Journal of Medical and Pharmaceutical Sciences","volume":"77 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140736114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-03DOI: 10.36348/sjmps.2024.v10i04.002
Mohammed Abdulrahman Al-Falah, Y. Medany, Mansoor Alnaim, Mareyah Alshaikh Husain, Mariam Sami Alshehab, Y. Al-Mulhim, J. AlRashada, A. Alarfaj, S. A. Almulhim, Abdulaziz Ali Alyousof, Hesham Alsuqair, Munirah Aldawsari
Objectives: To investigate the prevalence and mechanisms of atrial fibrillation (AF) among type 2 diabetes (T2D) patients. Methods: We conducted a thorough search of PubMed, SCOPUS, Web of Science, Google Scholar, and Science Direct to find pertinent literature. Rayyan QRCI was utilized during the entire process. Results: We included twelve studies with a total of 587,822 T2D patients and 299,957 (51%) were females. The prevalence of AF among T2D patients ranged from 0.2% to 41.63% with a total prevalence of 44936 (7.6%). The reported risk factors for developing AF among T2D patients were impaired glucose tolerance (IGT), men, obesity, elderly patients, those with lower socioeconomic backgrounds, those who currently smoked, people with reduced renal function, long-term BP fluctuation, and microvascular illness. Conclusion: Although the exact relationship between T2D and AF is still unclear, there is a significant correlation. Certain glycemic control studies indicate that therapeutic HbA1c levels in conjunction with well-controlled T2D do not significantly reduce the risk of new-onset AF in T2D patients. Further investigation is needed to fully comprehend the connection between T2D and AF. In the interim, healthcare professionals can treat people with T2D, AF, or possibly both illnesses at the same time according to accepted guidelines.
{"title":"The Relationship between the Incidence of Atrial Fibrillation and Patients with Type 2 Diabetes Mellitus: A Systematic Review","authors":"Mohammed Abdulrahman Al-Falah, Y. Medany, Mansoor Alnaim, Mareyah Alshaikh Husain, Mariam Sami Alshehab, Y. Al-Mulhim, J. AlRashada, A. Alarfaj, S. A. Almulhim, Abdulaziz Ali Alyousof, Hesham Alsuqair, Munirah Aldawsari","doi":"10.36348/sjmps.2024.v10i04.002","DOIUrl":"https://doi.org/10.36348/sjmps.2024.v10i04.002","url":null,"abstract":"Objectives: To investigate the prevalence and mechanisms of atrial fibrillation (AF) among type 2 diabetes (T2D) patients. Methods: We conducted a thorough search of PubMed, SCOPUS, Web of Science, Google Scholar, and Science Direct to find pertinent literature. Rayyan QRCI was utilized during the entire process. Results: We included twelve studies with a total of 587,822 T2D patients and 299,957 (51%) were females. The prevalence of AF among T2D patients ranged from 0.2% to 41.63% with a total prevalence of 44936 (7.6%). The reported risk factors for developing AF among T2D patients were impaired glucose tolerance (IGT), men, obesity, elderly patients, those with lower socioeconomic backgrounds, those who currently smoked, people with reduced renal function, long-term BP fluctuation, and microvascular illness. Conclusion: Although the exact relationship between T2D and AF is still unclear, there is a significant correlation. Certain glycemic control studies indicate that therapeutic HbA1c levels in conjunction with well-controlled T2D do not significantly reduce the risk of new-onset AF in T2D patients. Further investigation is needed to fully comprehend the connection between T2D and AF. In the interim, healthcare professionals can treat people with T2D, AF, or possibly both illnesses at the same time according to accepted guidelines.","PeriodicalId":21367,"journal":{"name":"Saudi Journal of Medical and Pharmaceutical Sciences","volume":"26 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140746174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-03-28DOI: 10.36348/sjmps.2024.v10i03.010
Md. Mahmudur Rahman, Sabina Parveen, Sabrina Sarah Alam
Background: The magnitude of health problems related to ear and nose in Bangladesh has not been estimated in a larger scale and very little is known about the prevalence and types of ENT diseases. Commonest cause of hearing impairment in our country is middle ear infection. Conductive type of deafness mostly occurs due to otitis media with or without its complications. Goal of primary health eare services is to achieve "Sound hearing by 2030" will never be achieved if we could not find out possible association of middle ear disease with other health conditions. Objective: To determine the prevalence of ear and nasal diseases in Bangladeshi patients. Methods: Two hundred patients complaining of middle ear discharge and or nasal symptoms were included in this study, to see the association of COM with nasal disorders. This cross sectional study was conducted in Dhaka Medical College Hospital from July 2012 to June 2014.Sample was taken by purposive sampling. Sample was divided into four groups as exposed and diseased, exposed and not diseased, not exposed diseased and not exposed and not diseased. Results: Two hundred patients were studied in the department of ENT and Head Neck Surgery of Dhaka Medical College Hospital complaining of either COM or Sinonasal disease. Among them 107 were female and 93 were male and male female ratio was 1:1.15. On analyzing age distribution it was ranging from 10 years to 50 years with mean age 30±7.86% clustering around 25 years. This study revealed that 65 % of COM is in the age group of 10-30 years. Conclusion: A study on the prevalence of the Ear Nose throat and Head and Neck diseases in developing country like Bangladesh can provide basic data which can be relevant and beneficial to the development of medical ENT curriculum in the regional setup and subsequent medical practice.
{"title":"Prevalence of Ear and Nasal Diseases in Bangladeshi Patients","authors":"Md. Mahmudur Rahman, Sabina Parveen, Sabrina Sarah Alam","doi":"10.36348/sjmps.2024.v10i03.010","DOIUrl":"https://doi.org/10.36348/sjmps.2024.v10i03.010","url":null,"abstract":"Background: The magnitude of health problems related to ear and nose in Bangladesh has not been estimated in a larger scale and very little is known about the prevalence and types of ENT diseases. Commonest cause of hearing impairment in our country is middle ear infection. Conductive type of deafness mostly occurs due to otitis media with or without its complications. Goal of primary health eare services is to achieve \"Sound hearing by 2030\" will never be achieved if we could not find out possible association of middle ear disease with other health conditions. Objective: To determine the prevalence of ear and nasal diseases in Bangladeshi patients. Methods: Two hundred patients complaining of middle ear discharge and or nasal symptoms were included in this study, to see the association of COM with nasal disorders. This cross sectional study was conducted in Dhaka Medical College Hospital from July 2012 to June 2014.Sample was taken by purposive sampling. Sample was divided into four groups as exposed and diseased, exposed and not diseased, not exposed diseased and not exposed and not diseased. Results: Two hundred patients were studied in the department of ENT and Head Neck Surgery of Dhaka Medical College Hospital complaining of either COM or Sinonasal disease. Among them 107 were female and 93 were male and male female ratio was 1:1.15. On analyzing age distribution it was ranging from 10 years to 50 years with mean age 30±7.86% clustering around 25 years. This study revealed that 65 % of COM is in the age group of 10-30 years. Conclusion: A study on the prevalence of the Ear Nose throat and Head and Neck diseases in developing country like Bangladesh can provide basic data which can be relevant and beneficial to the development of medical ENT curriculum in the regional setup and subsequent medical practice.","PeriodicalId":21367,"journal":{"name":"Saudi Journal of Medical and Pharmaceutical Sciences","volume":"83 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140370914","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hyper-IgE syndrome (also known as Job or Buckley syndrome) is a hereditary immune deficiency of autosomal dominant inheritance. It is clinically characterized by the occurrence of recurrent staphylococcal, skin abscesses, bacterial and fungal pneumopathies, and a significant increase in immunoglobulin E. Its association with systemic lupus erythematosus has been described, the mechanism of which involves the deposition of immune complexes. We report the case of an 11-year-old girl with hyper IgE syndrome who was admitted to our clinic with severe renal failure, diagnosed as lupus glomerulonephritis on kidney biopsy.
高免疫球蛋白E综合征（又称乔布或巴克利综合征）是一种常染色体显性遗传的遗传性免疫缺陷病。它的临床特点是反复发生葡萄球菌性皮肤脓肿、细菌性和真菌性肺炎，免疫球蛋白 E 显著增高。有报道称它与系统性红斑狼疮有关，其机制涉及免疫复合物的沉积。我们报告了一例患有高 IgE 综合征的 11 岁女孩的病例，她因严重的肾功能衰竭入院，肾活检诊断为狼疮肾小球肾炎。
{"title":"Lupic Glomerulonephritis in a Patient Presenting with Hyperimmunoglobulin E Syndrome: A Case Report","authors":"Pr Bouchoual Mohammed, Cherradi Ihsene, Pr Anibar Sara, Pr Jabrane Marouane, Pr Arrayhani Mohamed","doi":"10.36348/sjmps.2024.v10i03.009","DOIUrl":"https://doi.org/10.36348/sjmps.2024.v10i03.009","url":null,"abstract":"Hyper-IgE syndrome (also known as Job or Buckley syndrome) is a hereditary immune deficiency of autosomal dominant inheritance. It is clinically characterized by the occurrence of recurrent staphylococcal, skin abscesses, bacterial and fungal pneumopathies, and a significant increase in immunoglobulin E. Its association with systemic lupus erythematosus has been described, the mechanism of which involves the deposition of immune complexes. We report the case of an 11-year-old girl with hyper IgE syndrome who was admitted to our clinic with severe renal failure, diagnosed as lupus glomerulonephritis on kidney biopsy.","PeriodicalId":21367,"journal":{"name":"Saudi Journal of Medical and Pharmaceutical Sciences","volume":"120 35","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140380191","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-03-21DOI: 10.36348/sjmps.2024.v10i03.008
C. S, S. A, B. H, N. G, N. O, K. A, D. B, Reding R, Veyckemans F, C. Y
Meckel's diverticulitis or meckelitis is the infection of the Meckel's diverticulum. The aim of this work was to study the epidemiological, diagnostic, therapeutic and evolutionary aspects in the pediatric surgery department of the Nianankoro FOMBA hospital in Ségou, Mali. This was a retrospective study concerning observations between July 2010 and June 2012. We reported 5 observations in 2 years, representing a frequency of 2.5 cases per year. The average age was 6.6 years and the sex ratio was 1.5. Diagnostically, abdominal pain was the main reason for consultation followed by fever and vomiting. Physical examination found in all cases abdominal pain more or less associated with guarding in the right iliac fossa and peri-umbilical area. Abdominal bloating and contracture were noted in one case. There was hyperleukocytosis in all our 5 observations. The diagnosis was an operative discovery in 4 cases. Ultrasound was contributory in one case. Therapeutically, segmental resection of the small intestine removing the diverticulum, followed by immediate end-to-end anastomosis of the small intestine was the only technique performed in all our patients. The postoperative course was simple in 4 cases. A wall abscess with a favorable outcome was noted. Histological examination confirmed meckelitis at different stages (inflammatory, abscessed, gangrenous or necrotic). Gastric heterotopia was noted in one observation.
{"title":"Meckel's Diverticulitis: About 5 Pediatric Observations Collected at the Nianankoro FOMBA Hospital in Ségou, Mali","authors":"C. S, S. A, B. H, N. G, N. O, K. A, D. B, Reding R, Veyckemans F, C. Y","doi":"10.36348/sjmps.2024.v10i03.008","DOIUrl":"https://doi.org/10.36348/sjmps.2024.v10i03.008","url":null,"abstract":"Meckel's diverticulitis or meckelitis is the infection of the Meckel's diverticulum. The aim of this work was to study the epidemiological, diagnostic, therapeutic and evolutionary aspects in the pediatric surgery department of the Nianankoro FOMBA hospital in Ségou, Mali. This was a retrospective study concerning observations between July 2010 and June 2012. We reported 5 observations in 2 years, representing a frequency of 2.5 cases per year. The average age was 6.6 years and the sex ratio was 1.5. Diagnostically, abdominal pain was the main reason for consultation followed by fever and vomiting. Physical examination found in all cases abdominal pain more or less associated with guarding in the right iliac fossa and peri-umbilical area. Abdominal bloating and contracture were noted in one case. There was hyperleukocytosis in all our 5 observations. The diagnosis was an operative discovery in 4 cases. Ultrasound was contributory in one case. Therapeutically, segmental resection of the small intestine removing the diverticulum, followed by immediate end-to-end anastomosis of the small intestine was the only technique performed in all our patients. The postoperative course was simple in 4 cases. A wall abscess with a favorable outcome was noted. Histological examination confirmed meckelitis at different stages (inflammatory, abscessed, gangrenous or necrotic). Gastric heterotopia was noted in one observation.","PeriodicalId":21367,"journal":{"name":"Saudi Journal of Medical and Pharmaceutical Sciences","volume":" 34","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140388139","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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