Demographic and Clinical Characteristics of Endometrial Cancer in Northwestern Iran, Urmia: A Ten-Year Cross-Sectional Study

H. Ayatollahi, Elham Rajabi, R. Razavi, Samira Jahangard
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Abstract

Background: endometrial cancer is the most frequent genital cancer in women  in the developing nation. The purpose of this study was to investigate on  the demographic and clinical aspects of endometrial cancer, or to explain its epidemiology in patients admitted to Urmia's Kosar Hospital. Methods: From 2006 to 2016, the medical records of 179 hospitalized women with an initial diagnosis of endometrial cancer were analyzed in this cross-sectional research. The patients’ clinical and demographic information, including age, menstrual age, first visit reason, number of deliveries, menstrual pattern, history of previous disease in patients and their relatives, disease stage, clinical parameters (including WBC, Hb, and MCV), pathology type, and the presence or absence of metastasis was extracted from their medical records and analyzed. Results: The patients in our research had a mean age of more than 50 years. Nearly 80% of the patients were menopausal, and approximately 90% of the patients presented with bleeding complaints. Patients with endometrioid type adenocarcinoma had the highest frequency of pathology. Conclusion: Our findings show a high proportion of bleeding complaints among the patients evaluated, which might reflect the importance of this finding and help to guide the disease’s diagnosis and therapy. However, further research is needed to establish the epidemiology of this condition in the country.
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伊朗西北部尿毒症地区子宫内膜癌的人口学和临床特征:一项为期十年的横断面研究
背景:子宫内膜癌是发展中国家女性中最常见的生殖器癌。本研究的目的是调查子宫内膜癌的人口统计学和临床方面,或解释其在Urmia的Kosar医院入院患者中的流行病学。方法:对2006 - 2016年首次诊断为子宫内膜癌的179例住院妇女的病历进行横断面分析。从患者的病历中提取患者的临床和人口学信息,包括年龄、月经年龄、初诊原因、分娩次数、月经方式、患者及其亲属既往病史、疾病分期、临床参数(包括WBC、Hb、MCV)、病理类型、有无转移等,并进行分析。结果:本组患者平均年龄大于50岁。近80%的患者已绝经,约90%的患者出现出血主诉。子宫内膜样腺癌的病理发生率最高。结论:我们的研究结果显示,在评估的患者中出血主诉的比例很高,这可能反映了这一发现的重要性,并有助于指导疾病的诊断和治疗。然而,需要进一步研究以确定该国该病的流行病学。
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