Variations in Biochemical Parameters in Diabetic and Non-Diabetic Patients of Septicemia

Abstract

Septicemia is an infection caused by poisoning of blood by bacteria and is a prevalent disease in Pakistan. However, there is limited understanding of the pathogenesis of abnormal blood, liver and renal chemistry tests in septicemia. Objective: To determine variations in respective LFTs and RFTs and CBCs of diabetic and non-diabetic patients of septicemia. Methods: A descriptive, observational, cross-sectional research was directed, involving 101 participants diagnosed with septicemia. Study setting was Mayo Hospital Lahore. A specially designed Performa was used to record data, including liver function tests, renal function tests, and complete blood count for each patient. The data were analyzed using the latest version of SPSS. Results: In this study 45/101 patients of septicemia had diabetes. LFTs were also same for both non-diabetic and diabetic patients except Albumin which was low in diabetic patients but normal in non-diabetic patients. CBC were equally deranged in all diabetic and non-diabetic patients. Conclusions: This research provides important understandings into the variations of LFTs and RFTs and CBCs in diabetic and non-diabetic patients with septicemia. The findings suggest that while LFTs are similar between the two groups, there is a difference in albumin levels, highlighting the need for further investigation into the role of diabetes in septicemia.