Measles Infection and Vaccination Status against Measles in Children during 2019-2020: A Hospital Based Study in Chattogram

A. Ferdousi, M. Datta, Sayeda Shahnoor Hasina Mamtaz, Rifat Jahan, Salina Hoque, Rasheda Samad
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Abstract

Background: Despite widespread availability of a safe and cost-effective vaccine, Measles outbreak is reported from different regions of Bangladesh in the recent past. This study was aimed to Identify the related features of Measles infection in children during the upsurge of Measles infection in Chattogram during 2019-2020, when Bangladesh was about to achieve Measles elimination. Materials and methods: This prospective observational study included all the Measles infected children admitted in the Pediatric Ward of Chittagong Medical College Hospital, Chattogram during the period from September 2019-February 2020. In this hospital patients up to 12 years after neonatal period are admitted. Patients whose guardian did not give consent were excluded. Measles cases were diagnosed clinically according to case definition criteria by WHO. Demographic, clinical features, Measles vaccination status of both affected children & their mother and associated complications were recorded in a predesigned form. Data were analyzed and results were given in a tabulated form. The aim of this study was to evaluate the characteristics of Measles infection and their vaccination status in children during its upsurge in 2019-2020. Results: Affected children 13(20%) were suffered in spite of vaccination. Among the 65 affected children 44 (67.6%) were below one year of age, youngest one was 2 months old. Male to female ratio was 1.8:1. 80% (n=52) children were not vaccinated, 35 of them not yet attained the age of vaccination. 17 children attained the age but vaccination was delayed due to cough and cold, fever, bronchopneumonia or Measles itself. Complications were common among them, Bronchopneumonia 47 (72.3%) and Purulent conjunctivitis 38 (58.5%). There was no case fatality. Conclusion: Children are being affected by Measles before attaining the age of first dose of vaccination and incompletely vaccinated or unvaccinated children have a role in the upsurge of Measles. Chatt Maa Shi Hosp Med Coll J; Vol.22 (1); January 2023; Page 33-37
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2019-2020年儿童麻疹感染和麻疹疫苗接种状况:基于医院的统计图研究
背景:尽管安全且具有成本效益的疫苗广泛可用,但最近在孟加拉国不同地区报告了麻疹疫情。本研究旨在确定2019-2020年孟加拉国即将实现消除麻疹的Chattogram麻疹感染高峰期间儿童麻疹感染的相关特征。材料与方法:本前瞻性观察研究纳入2019年9月- 2020年2月期间在吉大港医学院附属医院儿科病房住院的所有麻疹感染儿童。在这家医院,新生儿期后12岁的病人都可以入住。未获得监护人同意的患者被排除在外。根据世卫组织病例定义标准对麻疹病例进行临床诊断。以预先设计的形式记录受影响儿童及其母亲的人口统计学、临床特征、麻疹疫苗接种状况和相关并发症。对数据进行分析,并以表格形式给出结果。本研究旨在评估2019-2020年麻疹高发期儿童麻疹感染特征及疫苗接种情况。结果:13例(20%)患儿接种疫苗后仍发病。65例患儿中,1岁以下44例(67.6%),最小1例2月龄。男女比例为1.8:1。80% (n=52)儿童未接种疫苗,其中35人尚未达到接种年龄。17名儿童达到年龄,但由于咳嗽和感冒、发烧、支气管肺炎或麻疹本身而推迟接种疫苗。并发症较多,支气管肺炎47例(72.3%),化脓性结膜炎38例(58.5%)。没有死亡病例。结论:麻疹发病年龄在首次接种疫苗年龄前,未完全接种或未接种疫苗的儿童是麻疹高发的重要原因。上海医科大学医学院;工程系(1);2023年1月;页面33-37
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