Triplet Pregnancy with a Complete Hydatidiform Mole and Two Live Fetuses: A Case Report

Pancieri Bárbara Gobetti, Ozório Carla Nassur, Gomes Carolina Viana Bueno, Ribeiro Ana Paula Alves, Vasconcellos Vitor Fiorin, Musiello Rubens Bermudes, Chambô Filho Antönio
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Abstract

Background: A complete hydatidiform mole (CHM) coexistent with a live fetus is rare; however, in a triplet pregnancy it is even rarer. In such cases, diagnosis is complex and often delayed, since unlike cases of a hydatidiform mole alone, the coexisting CHM often fails to be detected at ultrasound, while Β-hCG, a marker of the disease, is already elevated because of the multiple pregnancy. The risk of maternal complications and of progression to malignant gestational trophoblastic disease is significantly greater in cases of a complete mole. Case: The case reported here refers to a triplet pregnancy consisting of two viable fetuses and a CHM. Conclusion: Outcome was favorable for the two live fetuses; however, the hydatidiform mole progressed to an invasive mole, requiring chemotherapy. Remission was achieved successfully.
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三胞胎妊娠伴完整葡萄胎和两个活胎:1例报告
背景:完全葡萄胎(CHM)与活胎共存是罕见的;然而,在三胞胎怀孕中,这种情况更罕见。在这种情况下,诊断是复杂的,往往是延迟的,因为与单独的葡萄胎不同,共存的CHM通常无法在超声检查中发现,而Β-hCG,一种疾病的标志物,已经因为多胎妊娠而升高。在完全痣的情况下,母体并发症和进展为恶性妊娠滋养细胞疾病的风险明显更大。病例:这里报告的病例是指由两个可存活胎儿和一个CHM组成的三胞胎妊娠。结论:两例活胎结局良好;然而,葡萄胎发展为侵袭性葡萄胎,需要化疗。病情得以成功缓解。
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