Review of Modified Oral Solid Drug Delivery System and Recent Active Patents

S. Gaikwad, Shrikant K. Ainor, Narayan B. Lande, Salunkhe
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Abstract

A tablet is a solid dosage form containing active pharmaceutical ingredients (API) and various excipients. Different procedures, such as direct compression of powder mixtures, and dry and wet granulation technologies, are used to create distinct types of tablets. Tablet development is aided by technological advancements in the form of modified-release tablets. The modified release dosage form can be manufactured to obtain a specific pharmaceutical profile, the specific site of action and reduce the number of dose administrations using a variety of coating technologies. For modified released drug delivery, various sorts of patents are explored. The review's primary goal is to provide information on modified release formulations, formulation methodologies, current active patents based on modified release, and tablet coating technologies. The tablet is a common and convenient pharmaceutical dosage form. Recently, modified release drug administration has largely supplanted traditional tablet drug delivery technologies. The chrono pharmaceutical drug delivery can also involve modified drug delivery. Modified release tablets are used to boost the therapeutic impact of medicine by targeting the location of action on the illness condition. Modified-release tablets are very handy, easy to create, cost-effective, and do not require high-cost equipment, and they are gaining in popularity these days. Patents for modified-release tablet dosage formulations that are currently active were also discussed.
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改良口服固体给药系统及近期有效专利综述
片剂是含有活性药物成分(API)和各种赋形剂的固体剂型。不同的程序,如粉末混合物的直接压缩,干法和湿法造粒技术,用于制造不同类型的片剂。片剂的发展得益于技术的进步,即缓释片剂的形式。可以制造改性的释放剂型以获得特定的药物轮廓、特定的作用部位并使用各种涂层技术减少剂量施用的次数。对于改良的药物释放递送,探索了各种专利。该综述的主要目的是提供有关改性释放制剂、配方方法、基于改性释放的现行有效专利和片剂包衣技术的信息。片剂是一种常用、方便的药物剂型。最近,改良释放给药已经在很大程度上取代了传统的片剂给药技术。计时药物递送还可以涉及修饰药物递送。改良缓释片是用来提高药物的治疗效果,通过针对作用部位的疾病状况。修改释放平板电脑非常方便,易于制作,成本效益高,不需要昂贵的设备,这些天它们越来越受欢迎。还讨论了目前有效的缓释片剂型的专利。
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