Metabolites from Fungi 15. New Isocoumarins from an Endophytic Fungus Isolated from the Canadian Thistle Cirsium arvense

K. Krohn, U. Flörke, M. S. Rao, K. Steingröver, H. Aust, S. Draeger, B. Schulz
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引用次数: 51

Abstract

Abstract One known (1) and five new polyketide metabolites (2-6) were isolated from the culture extract of an endophytic fungus. Mycelia sterila, from the Canadian thistle Cirsium arvense. Compounds 1-4 are members of the isocoumarin family, whereas metabolite 5 is a dihydrobenzofuran and 6 has an open chain structure. All compounds have an unusual methyl group at the aromatic ring that does not fit into the usual polyketide pattern.
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真菌的代谢物加拿大蓟内生真菌中新的异香豆素
摘要从一种内生真菌的培养液中分离到1个已知的(1)和5个新的聚酮代谢产物(2-6)。无菌菌丝体,取自加拿大蓟。化合物1-4是异香豆素家族的成员,而代谢物5是二氢苯并呋喃,6具有开链结构。所有化合物的芳香环上都有一个不寻常的甲基,不符合通常的聚酮模式。
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