Sickle Cell Disease and COVID-19

L. Moradi
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Abstract

Context: The COVID-19 pandemic emerged in China and spread to the majority of countries worldwide, causing numerous health problems and restrictions on the people’s lifestyles. The complications of this disease can be much more severe in patients who have a weakened immune system or a chronic disease. Sickle cell disease is a genetic disorder in which the immune system is impaired. Exposure to COVID-19 will have severe consequences in the sickle cell disease patients. In this study aimed to investigate the relationship between this disease with the COVID-19 pandemic. Evidence Acquisition: Embase, Scopus, Pub Med databases were reviewed. Keywords were combined as (“COVID19” OR “Coronavirus” AND “Anemia sickle Cell” OR “Sickle cell disease”). The results of related articles were used. Results: At the time of the COVID-19 pandemic, chronic patients and those with weakened immune systems need to be more socially inclined to be less exposed to the COVID-19 virus. Conclusions: When producing the COVID vaccine, high-risk groups such as sickle cell anemia patients should be given priority.
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镰状细胞病和COVID-19
背景:新冠肺炎疫情从中国开始蔓延到世界大多数国家,给人们的健康带来了诸多问题,也给人们的生活方式带来了诸多限制。对于免疫系统较弱或患有慢性疾病的患者,这种疾病的并发症可能会严重得多。镰状细胞病是一种免疫系统受损的遗传性疾病。暴露于COVID-19将对镰状细胞病患者产生严重后果。本研究旨在探讨该疾病与COVID-19大流行的关系。证据获取:检索Embase、Scopus、Pub Med数据库。关键词组合为(“covid - 19”或“冠状病毒”与“贫血镰状细胞”或“镰状细胞病”)。采用相关文献的结果。结果:在新冠肺炎大流行期间,慢性病患者和免疫系统较弱的人群需要更多的社会倾向,以减少新冠病毒的暴露。结论:在生产新冠肺炎疫苗时,应优先考虑镰状细胞性贫血患者等高危人群。
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