Flavonoids: A vital resource in healthcare and medicine

Abstract

There are many biological resources in nature that are essential in relation to health care. Due to their flexible health benefits documented in various epidemiological studies, there has been increasing interest in research on flavonoids from plant sources. Since flavonoids are directly related to human dietary ingredients and health, structure and function relationships need to be evaluated. Flavonoids bioavailability, metabolism, and biological activity depends on the composition, total number of hydroxyl groups, and functional group substitution regarding their nuclear structure. Fruits and vegetables, together with tea and wine, are the primary dietary sources of flavonoids for humans. This review article primarily focusses on demarcating the importance of flavonoids which shows many pharmacological actions by acting as anti-cancer, anti-oxidant, anti-hypertensive and anti-cholinesterase agents. These flavonoids had shown positive results in treatment of pregnancy induced disorders. We also tried to discuss few studies which proves the efficiency of flavonoids to treat COVID-19. They had also been proved to show greater potential in treatment of Neurodegenerative diseases. Nanomedicine also has a greater part to play in near future as it helps flavonoids show effective targeted drug delivery. acute and short-term action, flavonoids improve endothelial functions. 54-57 Improving endothelial dependent and nitric oxide dependent vasodilation has been suggested as one of the possible mechanisms for involving flavonoids in endothelial and vascular function. The endothelial function change may also lead to lower blood pressure.