Diagnostics, monitoring and treatment of arterial hypertension in children

I. Karimdzhanov, G. Iskanova, N. A. Isrаilova
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Abstract

   The review presents material on the current relevance of AH in children. The prevalence of AH in overweight and obese children aged 6-18 years is 27–47 %, while secondary arterial hypertension remains dominant, especially in children younger than 5 years. AH is a major risk factor for atherosclerosis and cardiovascular disease in adults. The onset of these diseases may occur in childhood or adolescence. The use of modern methods to monitor and control BP is crucial for improving the management of AH and preventing damage to target organs. Twenty-four-hour BP measurements are an important tool in determining the prognosis and treatment of children with AH. AH in children can be classified as primary or essential if there is no identifiable cause, or as secondary AH when it arises from a specific cause. The incidence of primary arterial hypertension increases with age, whereas secondary arterial hypertension predominates in early childhood. The secondary causes of AH also depend on the age of the patient. Thus 34-79 % of patients with secondary forms of arterial hypertension have renal parenchymal disease and impaired renal structure. Signs of AH include headache, visual disturbances, dizziness and nosebleeds. Dyspnoea on exercise, facial paralysis and seizures indicate target organ damage. In children with obesity, diabetes, renal insufficiency, aortic coarctation/repaired coarctation and those receiving medication causing AH, BP should be measured at every visit to the physician. Therapeutic lifestyle changes are an early therapy in the treatment of AH in children. IAPs, BCAAs, BRAs and thiazide diuretics are the most effective drugs for AH in children.
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儿童高血压的诊断、监测和治疗
这篇综述介绍了目前儿童AH相关性的材料。6-18岁超重和肥胖儿童AH患病率为27 - 47%,而继发性动脉高血压仍占主导地位,尤其是5岁以下儿童。AH是成人动脉粥样硬化和心血管疾病的主要危险因素。这些疾病可能发生在儿童或青少年时期。使用现代方法监测和控制血压对于改善AH的管理和防止目标器官的损害至关重要。24小时血压测量是确定AH患儿预后和治疗的重要工具。如果没有可识别的病因,儿童AH可分为原发性或原发性AH,当其由特定原因引起时可分为继发性AH。原发性动脉高血压的发病率随着年龄的增长而增加,而继发性动脉高血压主要发生在儿童早期。AH的继发原因也取决于患者的年龄。因此,34- 79%的继发性动脉高血压患者有肾实质疾病和肾结构受损。AH的症状包括头痛、视觉障碍、头晕和流鼻血。运动时呼吸困难、面瘫和癫痫发作表明目标器官受损。对于肥胖、糖尿病、肾功能不全、主动脉缩窄/修复性缩窄以及接受药物治疗导致AH的儿童,应在每次就诊时测量血压。治疗性生活方式的改变是治疗儿童AH的早期治疗方法。IAPs、BCAAs、bra和噻嗪类利尿剂是治疗儿童AH最有效的药物。
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