Early Rehabilitation Provided by Specialized Physical Therapist in an Emergency Center Reduces Pulmonary Complications in Patients with Sepsis: A Retrospective Cohort Study

Y. Sakai, Shuhei Yamamoto, T. Karasawa, Masaaki Sato, K. Nitta, Mayumi Okada, Shota Ikegami, H. Imamura, H. Horiuchi
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Abstract

Early rehabilitation methods, including postural changes and respiratory physical therapies, have been shown to prevent pulmonary complications; however, strategies to prevent pulmonary complications in sepsis patients remain poorly defined. This clinical study was to evaluated if early rehabilitation provided by specialized physical therapist in an emergency center could reduce respiratory complications in sepsis patients. We evaluated sepsis patients for demographic characteristics, the number of days until rehabilitation, and the incidence of pulmonary complications. Kaplan-Meier curves were constructed to analyze the incidence of pulmonary complications for the study sample stratified by specialized physical therapists. Cox regression analysis examined the relationship between early rehabilitation provided by specialized physical therapists and the incidence of pulmonary complications. The number of days until rehabilitation was significantly shortened after assigning a specialized physical therapist. Assigning specialized physical therapist was significantly associated with pulmonary complications for sepsis patients and, in the multivariable model, specialized physical therapists (hazard ratio=0.34; 95%confidence interval=0.16-0.74; p=0.006) and the number of days until rehabilitation (hazard ratio=1.12; 95% confidence interval=1.08-1.19; p=0.047) were significantly associated with pulmonary complications. Early rehabilitation decreased the incidence of pulmonary complications in sepsis patients. [University Hospital Medical Information Network Clinical Trials Registry, number UMIN000039793 (2020/3/12)].
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急诊中心专业物理治疗师提供的早期康复可减少脓毒症患者的肺部并发症:一项回顾性队列研究
早期康复方法,包括体位改变和呼吸物理治疗,已被证明可以预防肺部并发症;然而,预防脓毒症患者肺部并发症的策略仍然不明确。本临床研究旨在评估急诊中心专业物理治疗师提供的早期康复是否可以减少败血症患者的呼吸并发症。我们评估了脓毒症患者的人口学特征、康复天数和肺部并发症的发生率。构建Kaplan-Meier曲线来分析由专业物理治疗师分层的研究样本的肺部并发症发生率。Cox回归分析检验了专业物理治疗师提供的早期康复与肺部并发症发生率之间的关系。指派专门的物理治疗师后,康复的天数显著缩短。指定专门的物理治疗师与脓毒症患者的肺部并发症显著相关,在多变量模型中,专门的物理治疗师(风险比=0.34;95%置信区间= 0.16 - -0.74;P =0.006)和康复天数(风险比=1.12;95%置信区间=1.08-1.19;P =0.047)与肺部并发症显著相关。早期康复治疗可降低脓毒症患者肺部并发症的发生率。[大学医院医学信息网临床试验注册,编号:UMIN000039793(2020/3/12)]。
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