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Effect of Knee Valgus Angle during Single Leg Squat and Horizontal Hop for Distance in Patients with Patellofemoral Pain and Controls 膝外翻角对髌股疼痛患者单腿深蹲和水平跳距离的影响及控制
Pub Date : 2021-06-08 DOI: 10.4236/IJCM.2021.126023
Hussain Ghulam
Background: Patellofemoral pain (PFP) is considered one of the most common dysfunctions of the lower extremities. Faulty lower limb mechanics and increased of knee valgus on loaded tasks are believed to play an important role in the development of PFP. Objective: To figure out if male PFP patients during single leg horizontal hop for distance and squat with greater knee valgus than controls, and if the nature of the task changes the angles of knee valgus. Methods: Twenty males with unilateral PFP formed the patient group and forty-five asymptomatic males formed the control group. Two dimensional (2-D) frontal plane projection angle (FPPA) was used during single leg squatting and horizontal hop for distance tasks. Results: For the single leg squat, the mean of 6.96°, 9.80°, 15.04° was reported in the control, PFP asymptomatic knee, and PFP symptomatic knee, respectively. For the single leg horizontal hop for distance, the mean of 11.63°, 13.72°, 19.17° was reported in the control, PFP asymptomatic knee, and PFP symptomatic knee, respectively. These differences were significant (p < 0.002) for both tasks. Conclusions: Patients with PFP represented with greater knee valgus angle than what was found in either their asymptomatic limb or in the control group.
背景:髌股痛(PFP)被认为是最常见的下肢功能障碍之一。下肢力学缺陷和负重任务时膝关节外翻的增加被认为在PFP的发展中起重要作用。目的:了解男性PFP患者在单腿水平跳距离和深蹲运动中是否有较大的膝关节外翻,以及该运动的性质是否改变了膝关节外翻的角度。方法:男性单侧PFP患者20例为患者组,男性无症状患者45例为对照组。在单腿深蹲和水平跳跃的距离任务中使用二维额平面投影角(FPPA)。结果:单腿深蹲时,对照组、PFP无症状膝关节和PFP有症状膝关节的平均深蹲度分别为6.96°、9.80°、15.04°。对于单腿水平跳距离,对照组、PFP无症状膝关节和PFP有症状膝关节的平均跳距分别为11.63°、13.72°和19.17°。两项任务的差异均显著(p < 0.002)。结论:与无症状肢体或对照组相比,PFP患者的膝关节外翻角度更大。
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引用次数: 0
Autoimmune Hepatitis Prevalence among Patients from Saudi Arabia with Chronic Liver Disease Referred for Transient Elastography 沙特阿拉伯慢性肝病患者的自身免疫性肝炎患病率进行瞬时弹性成像
Pub Date : 2021-06-08 DOI: 10.4236/IJCM.2021.126022
Rajaa Alshanketi, Reem Jabbad, B. Baghlaf, Romaysaa Al-Yamani, Majed A Al-Sahafi, Hisham O Akbar, H. Fallatah
Background and study aim: Autoimmune hepatitis (AIH) is a chronic liver disease that can lead to progressive liver damage. The prevalence of AIH among the general population and among chronic liver disease (CLD) patients is variable worldwide. Currently, no published data on the prevalence of AIH among Saudi or among liver disease patients from the region. In this study, we aimed to assess the prevalence of AIH among CLD patients who were referred for transient elastography (FibroScan) in Saudi Arabia. Patients and methods: A retrospective study was conducted among CLD patients who had a transient elastography (FibroScan) during the 3-year study period. We obtained demographic data and test results for serum alanine aminotransferase (ALT), bilirubin, hemoglobin (Hgb), platelets, and international normalized ratio (INR) from all patients. We compared the results of the AIH patients to those of the non-AIH patients with CLD. In addition, for AIH patients, we measured serum immunoglobulin G (IgG), antinuclear antibody (ANA), smooth muscle antibody (SMA) and ALT at 2 - 6 weeks and at 3 - 4 months. Results: We included 494 patients, who were predominantly female (271 (60%)) and Saudi (299 (60.5%)). Thirty patients (6.1%) had AIH, which represented the 4th most common liver disease. Compared to non-AIH patients, AIH patients were younger (mean ages 49.9 years, SD 14.22 years, and 40.4 years, SD 13.94 years, respectively, P = 0.001). Patients with AIH had significantly lower Hgb and platelets (P = 0.008 for both) and higher ALT, bilirubin and INR (P = 0.05, 0.047 and 0.019, respectively). More than 50% of the AIH patients had cirrhosis. Older age was not associated with advanced disease stage among the AIH patients (P th most common cause of CLD in patients referred for transient elastography in Saudi Arabia. AIH tends to be severe in patients at a young age, with a marked biochemical response to steroids and azathioprine treatment.
背景与研究目的:自身免疫性肝炎(AIH)是一种慢性肝脏疾病,可导致进行性肝损害。AIH在普通人群和慢性肝病(CLD)患者中的患病率在世界范围内是可变的。目前,没有公布的关于沙特阿拉伯或该地区肝病患者中AIH患病率的数据。在这项研究中,我们旨在评估沙特阿拉伯转介进行瞬时弹性成像(FibroScan)的CLD患者中AIH的患病率。患者和方法:在为期3年的研究期间,对进行过短暂弹性成像(FibroScan)的CLD患者进行了回顾性研究。我们获得了所有患者的人口统计学数据和血清丙氨酸转氨酶(ALT)、胆红素、血红蛋白(Hgb)、血小板和国际标准化比率(INR)的检测结果。我们比较了AIH患者与非AIH CLD患者的结果。此外,对于AIH患者,我们在2 - 6周和3 - 4个月时检测血清免疫球蛋白G (IgG)、抗核抗体(ANA)、平滑肌抗体(SMA)和ALT。结果:我们纳入了494例患者,主要是女性(271(60%))和沙特(299(60.5%))。30例患者(6.1%)患有AIH, AIH是第四大常见肝脏疾病。与非AIH患者相比,AIH患者更年轻(平均年龄49.9岁,SD 14.22岁;平均年龄40.4岁,SD 13.94岁,P = 0.001)。AIH患者Hgb和血小板均显著降低(P = 0.008), ALT、胆红素和INR均显著升高(P分别= 0.05、0.047和0.019)。超过50%的AIH患者有肝硬化。在沙特阿拉伯接受短暂弹性成像的AIH患者中,年龄较大与疾病晚期无关(AIH是CLD的最常见原因)。AIH在年轻患者中往往是严重的,对类固醇和硫唑嘌呤治疗有明显的生化反应。
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引用次数: 0
Effect of Bundle Care on Deep Venous Thrombosis in Patients Received Renal Biopsy 捆绑护理对肾活检患者深静脉血栓形成的影响
Pub Date : 2021-05-19 DOI: 10.4236/IJCM.2021.125017
Ying-xue Zhong, Yuan He, Ling Liu, Lexiaochuan Wen, Fanna Liu, Yu Chen
Objective: To explore the effect of bundle care on the incidence of venous thromboembolism (VTE) in patients who received renal biopsy, and provide reference for clinical care. Methods: 300 patients with nephrotic syndrome who received renal biopsy in our hospital from February 2018 to August 2020 were selected and randomly divided into the observation group and the control group, with 150 patients in each group. In the control group, patients were given routine care: informing the precautions before and after operation, observing the changes of vital signs and bleeding after operation, etc. In the observation group, patients were given bundle care intervention, including preoperative, intraoperative and postoperative routine care, ankle pump exercise, Intermittent Pneumatic Compression (IPC) treatment and psychological care. The incidence of lower-limb venous thrombosis was compared between the two groups. Results: The incidence of deep venous thrombosis in the observation group was lower than that in the control group (P < 0.05), 1 case (0.6%) in the observation group and 8 cases (5.3%) in the control group; the peak velocity and mean velocity of lower-limb venous blood flow in the observation group were higher than those in the control group; the average length of stay in the observation group was less than that in the control group, and the satisfaction degree in the observation group was higher than that in the control group. The differences were statistically significant (P < 0.05). Conclusion: For patients who received renal biopsy, bundle care can help improve the peak velocity and mean velocity of venous blood flow, reduce the incidence of VTE, the average length of stay, and social costs, relieve their pain, and improve satisfaction degree of care; moreover, it plays an important role in reducing the incidence of deep venous thrombosis.
目的:探讨捆绑护理对肾活检患者静脉血栓栓塞(VTE)发生率的影响,为临床护理提供参考。方法:选择2018年2月至2020年8月在我院行肾活检的肾病综合征患者300例,随机分为观察组和对照组,每组150例。对照组给予患者常规护理:告知术前、术后注意事项、观察术后生命体征及出血变化等。观察组患者给予综合护理干预,包括术前、术中、术后常规护理、踝关节泵运动、间歇气动压缩(IPC)治疗和心理护理。比较两组下肢静脉血栓的发生率。结果:观察组深静脉血栓发生率低于对照组(P < 0.05),观察组1例(0.6%),对照组8例(5.3%);观察组下肢静脉血流量峰值流速和平均流速均高于对照组;观察组患者平均住院时间小于对照组,患者满意度高于对照组。差异有统计学意义(P < 0.05)。结论:对于肾活检患者,采用束式护理有助于提高静脉血流峰值流速和平均流速,降低静脉血栓栓塞发生率、平均住院时间和社会成本,减轻患者痛苦,提高护理满意度;此外,它在降低深静脉血栓形成的发生率方面具有重要作用。
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引用次数: 0
Clinical Application of Quantitative Nursing for Lower Cranial Nerves Injury after Cerebellopontine Angle Tumors 定量护理在桥小脑角肿瘤后下颅神经损伤中的临床应用
Pub Date : 2021-05-19 DOI: 10.4236/IJCM.2021.125018
Yanfei Zhang, Jingxin Fu, Qichao Chen, Yedong Wan, Ming Zhao, Longbiao Xu
Objective: To retrospectively analyze the clinical utility of quantitative nursing measures of 10 cases of lower cranial nerves injury after cerebellopontine angle tumors surgery to provide the experience for improving the recovery rate and living quality of these patients. Methods: The clinical data of 10 cases of lower cranial nerves injury after cerebellopontine angle tumors surgery was analyzed. For problems such as dysphagia and dyspnea of these patients, the nursing care focused on strict monitoring, timely oxygen inhalation nursing, posture nursing, ventilator nursing, swallowing function training, etc. Results: After received quantitative care, 10 patients with lower cranial nerves injury after cerebellopontine angle tumors surgery were recovered well, and their symptoms such as dysphagia and dyspnea were gradually improved and safely discharged. Conclusion: Lower cranial nerves injury is one of the serious complications after removal of cerebellopontine angle tumors, which impacts the life and health of patients. Caregivers should accurately understand and analyze the symptoms, and quantitative and targeted nursing measures for posterior cranial nerves injury are helpful in the postoperative rehabilitation of patients and improve their living quality.
目的:回顾性分析10例桥小脑角肿瘤术后下颅神经损伤定量护理措施的临床应用,为提高患者的治愈率和生活质量提供经验。方法:分析10例脑桥小脑角肿瘤术后下颅神经损伤的临床资料。针对这些患者出现的吞咽困难、呼吸困难等问题,护理重点是严格监护、及时吸氧护理、体位护理、呼吸机护理、吞咽功能训练等。结果:10例桥小脑角肿瘤术后下颅神经损伤患者经定量护理后恢复良好,吞咽困难、呼吸困难等症状逐渐改善,安全出院。结论:下颅神经损伤是桥小脑角肿瘤切除术后的严重并发症之一,严重影响患者的生命和健康。护理人员应准确认识和分析症状,对后颅神经损伤采取定量、有针对性的护理措施,有助于患者术后康复,提高患者的生活质量。
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引用次数: 1
Racial Differences Effects on Oral Health and Periodontal Diseases Extent, Staging and Grading among the Multi-Ethnic Expatriates in Aseer Region, Saudi Arabia 种族差异对沙特阿拉伯阿西尔地区多民族外籍人士口腔健康和牙周病程度、分期和分级的影响
Pub Date : 2021-04-16 DOI: 10.4236/IJCM.2021.124015
M. Al-Abdaly, S. Alqahtani, Shaker Saleh M. Alosman, G. Alqahtani
Background: Given the increase in the numbers of expatriates in Saudi Arabia and the shortage of information about expatriates’ oral health and periodontal disease severity and progression. Objectives: This study aimed to evaluate the effects of the racial differences on oral health and periodontal disease extent, staging, and grading among the multi-ethnic expatriates in the Aseer region, Saudi Arabia. Materials and Methods: This cross-sectional study was carried out on 300 expatriates in Aseer region, Saudi Arabia. They were divided into three equal racial different groups (n = 100), Arabs (AR), Asians (AS), and Africans (AF). The interviews of all participants were completed then the clinical examinations of periodontal diseases extent, staging, and grading parameters were performed. Statistical analysis was done by ANOVA test, Tukey’s test, and Chi-square test. The statistical significance level was determined at p < 0.05. Results: There were statistically significant differences in the comparison between the three ethnic/racial groups in clinical parameters except in GBI, PCR, FI, TFO, and BC, where there were no statistically significant differences in the comparison between the three ethnic/racial groups. There were differences associated with age, gender, smoking, and diabetes, without statistically significant differences among the three racial groups. Conclusion: We concluded that most participants in this study had a generalized severe grade 4 plaque-induced gingivitis and localized periodontitis stage III grade B.
背景:鉴于沙特阿拉伯外籍人士数量的增加以及外籍人士口腔健康和牙周病严重程度和进展的信息短缺。目的:本研究旨在评估种族差异对沙特阿拉伯阿西尔地区多民族外籍人士口腔健康和牙周病程度、分期和分级的影响。材料和方法:本横断面研究对沙特阿拉伯阿西尔地区的300名外籍人士进行了调查。他们被分成三个平等的种族不同组(n = 100),阿拉伯人(AR),亚洲人(AS)和非洲人(AF)。对所有参与者进行访谈,并进行牙周病程度、分期和分级参数的临床检查。统计学分析采用ANOVA检验、Tukey检验和卡方检验。p < 0.05为差异有统计学意义。结果:除GBI、PCR、FI、TFO、BC外,3个民族/种族间临床参数比较差异均有统计学意义,其中3个民族/种族间比较差异无统计学意义。这些差异与年龄、性别、吸烟和糖尿病有关,在三个种族群体之间没有统计学上的显著差异。结论:我们得出的结论是,本研究的大多数参与者患有广泛性严重4级菌斑性牙龈炎和局限性III期B级牙周炎。
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引用次数: 0
Comparison of Nasal and Frontal BIS Monitoring in Neurosurgery: Does the Site of Sensor Placement Affect the BIS Values? 神经外科中鼻部和额部BIS监测的比较:传感器放置位置是否影响BIS值?
Pub Date : 2021-03-16 DOI: 10.4236/IJCM.2021.123012
K. Hajiyeva, B. Meço, Ç. Y. Güçlü, D. Yorukoglu, B. Doganay, M. Oral
Background and Goal of Study: Intraoperative awareness is a serious but preventable complication of general anaesthesia. Bispectral index (BIS) is the most widely used method monitoring anaesthesia depth. BIS monitoring requires attachment of forehead sensors, which poses a challenge when the surgical field involves the forehead. We aimed to compare the gold standard forehead position of BIS sensors with an alternative position across the nasal dorsum for neurosurgical procedures. Materials and Methods: After ethical committee approval and informed consent were obtained, 62 patients were enrolled in this prospective observational study. Frontal and nasal BIS values were compared in all patients. Results and Discussion: The mean BIS value from frontal versus nasal sensors was 49 ± 22 and 49 ± 21 respectively (n: 62). These values were statistically correlated (ICC 0.78, p < 0.001) indicating that nasal BIS measurement does not present a disadvantage for routine use when needed. Conclusion: Our data reveal that for measuring anesthesia depth, BIS sensor placement on the nasal dorsum shows comparable efficiency in comparison to standard frontal measurements
研究背景和目的:术中意识是全身麻醉的一种严重但可预防的并发症。双谱指数(BIS)是目前应用最广泛的麻醉深度监测方法。BIS监测需要附加前额传感器,当手术野涉及前额时,这是一个挑战。我们的目的是比较BIS传感器的金标准前额位置与神经外科手术中横跨鼻背的替代位置。材料和方法:经伦理委员会批准并获得知情同意后,62例患者入组本前瞻性观察性研究。比较所有患者的额部和鼻腔BIS值。结果与讨论:额部与鼻部传感器的平均BIS值分别为49±22和49±21 (n: 62)。这些值具有统计学相关性(ICC 0.78, p < 0.001),表明在需要时,鼻腔BIS测量并不存在常规使用的劣势。结论:我们的数据显示,在测量麻醉深度时,BIS传感器放置在鼻背与标准额部测量相比具有相当的效率
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引用次数: 1
Influence of Age on the Clinical and Prognostic Features of Tetanus in Mali 年龄对马里破伤风临床及预后特征的影响
Pub Date : 2021-03-16 DOI: 10.4236/IJCM.2021.123010
M. Kaboré, I. Konaté, Y. Cissoko, J. Dembélé, M. Soumaré, A. Fofana, D. Sogoba, O. Magassouba, H. Meli, Abdoulaye Zaré, Mohamed Cissé, B. Coulibaly, H. Issa, Fodé Kouyaté, J. Dembele, S. Dao
Background: The regression of post-vaccination immunity with age exposes elderly subjects to certain infectious diseases, in particular tetanus. The aim was to compare the clinical and prognostic features of tetanus according to the age of patients. Methodology: Analytical study of the files of patients hospitalized for tetanus in the Infectious Diseases Department at Point “G” University Teaching Hospital from 2013 to 2019 with retrospective collection. According to age, three groups of patients were formed: group I (<18 years), group II (18 - 59 years) and group III (≥60 years). The study variables were socio-demographic, clinical and prognostic. The One-way ANOVA and Chi-square statistical tests were applied with a significance level p = 0.05. Results: In total, 202 cases of tetanus were recorded or 7.3% of admissions. The mean age was 41.9 ± 15.6 years (range, 6 and 85 years) with a sex ratio of 19.2. According to the age grouping, group II was predominant (79.2%) followed by group III (14.9%) with respective mean ages of 39.2 ± 10.6 and 67.3 ± 6.5 and sex ratio of 39 and 29. Workers (33.3%), farmers (25.8%), traders (19.7%) and drivers (7.1%) represented the most important occupations most at risk. Clinically, bad general condition (p < 0.001), trismus (p = 0.001), dysphagia (p = 0.009) and complications during hospitalization (p = 0.028) were seen more frequently in group III patients compared to younger ones. From a prognostic point of view, patients in group III were at greater risk to develop a severe form of tetanus (p = 0.021) with higher mortality compared to other age groups (p < 0.001). Conclusion: Tetanus is more prevalent in men. Complications and mortality increase with age. It is important to include booster immunization of adults in existing national programs in order to reduce disease-related morbidity and mortality in this age group.
背景:随着年龄的增长,疫苗接种后免疫力的回归使老年人暴露于某些传染病,特别是破伤风。目的是根据患者的年龄比较破伤风的临床和预后特征。方法:对2013 - 2019年G点大学教学医院感染性疾病科收治的破伤风患者档案进行回顾性收集分析。根据患者年龄分为三组:I组(<18岁)、II组(18 ~ 59岁)和III组(≥60岁)。研究变量包括社会人口学、临床和预后。采用单因素方差分析和卡方统计检验,显著性水平p = 0.05。结果:本院共收治破伤风202例,占入院率的7.3%。平均年龄41.9±15.6岁(范围6 ~ 85岁),性别比19.2。按年龄分,以II组(79.2%)居多,其次为III组(14.9%),平均年龄分别为39.2±10.6和67.3±6.5,性别比分别为39和29。工人(33.3%)、农民(25.8%)、贸易商(19.7%)和司机(7.1%)是最重要的高危职业。临床中,III组患者一般状况不良(p < 0.001)、唇腭裂(p = 0.001)、吞咽困难(p = 0.009)和住院期间并发症(p = 0.028)发生率高于年轻组。从预后角度来看,与其他年龄组相比,III组患者发生严重破伤风的风险更大(p = 0.021),死亡率更高(p < 0.001)。结论:破伤风以男性为主。并发症和死亡率随年龄增长而增加。重要的是,在现有的国家规划中纳入成人加强免疫,以减少这一年龄组的疾病相关发病率和死亡率。
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引用次数: 0
A Nasal Localization of Abrikossof Tumor Observed to Yaounde Reference Hospital 雅温得参比医院一例鼻部肿瘤定位观察
Pub Date : 2021-03-16 DOI: 10.4236/IJCM.2021.123009
Yves Christian Andjock Nkouo, Antoine Bola Siafa, D. Eko, W. Anoumedem, F. Djomou, R. Njock
Background/Aim: Abrikossof’s tumor or granular cell tumor is a rare tumor. The cervicofacial localization is the most common. The aim of this report case was to show a rare case of nasal localization, to the 48-year old patient, treated in poor medical condition. Case presentation: The patient consults late with enormous nasal mass involving for five years. After biopsy and facial CT-scan, a surgical procedure was performed. The evolution was good and the final pathology confirms the diagnosis. The objective of this case report was to show the originality of the presentation and the difficulties for management in poor medical environment. Conclusion: Abrikossof’s tumor is a rare benign tumor but whose preferential development occurs at the expense of the ENT sphere. Large forms remain the preserve of poor environments. The diagnosis is pathological and the treatment is surgical.
背景/目的:abrikossofs肿瘤或颗粒细胞瘤是一种罕见的肿瘤。颈面定位是最常见的。本报告的目的是显示一个罕见的病例鼻腔定位,48岁的病人,治疗条件差。病例介绍:患者就诊较晚,伴有巨大鼻肿块累及5年。在活检和面部ct扫描后,进行手术治疗。进展良好,最终病理证实了诊断。本病例报告的目的是显示独创性的表现和困难的管理在恶劣的医疗环境。结论:abrikossofs肿瘤是一种罕见的良性肿瘤,其优先发展是以牺牲耳鼻喉球为代价的。大型形式仍然是恶劣环境的保护。病理诊断,手术治疗。
{"title":"A Nasal Localization of Abrikossof Tumor Observed to Yaounde Reference Hospital","authors":"Yves Christian Andjock Nkouo, Antoine Bola Siafa, D. Eko, W. Anoumedem, F. Djomou, R. Njock","doi":"10.4236/IJCM.2021.123009","DOIUrl":"https://doi.org/10.4236/IJCM.2021.123009","url":null,"abstract":"Background/Aim: Abrikossof’s tumor or granular cell tumor is a rare tumor. The cervicofacial localization is the most common. The aim of this report case was to show a rare case of nasal localization, to the 48-year old patient, treated in poor medical condition. Case presentation: The patient consults late with enormous nasal mass involving for five years. After biopsy and facial CT-scan, a surgical procedure was performed. The evolution was good and the final pathology confirms the diagnosis. The objective of this case report was to show the originality of the presentation and the difficulties for management in poor medical environment. Conclusion: Abrikossof’s tumor is a rare benign tumor but whose preferential development occurs at the expense of the ENT sphere. Large forms remain the preserve of poor environments. The diagnosis is pathological and the treatment is surgical.","PeriodicalId":14201,"journal":{"name":"International Journal of Physical Medicine and Rehabilitation","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77399441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Analysis of 154 T4 Colorectal Cancer Patients with Peritoneal Carcinomatosis Treated by Surgery 手术治疗T4结直肠癌腹膜癌154例分析
Pub Date : 2021-02-22 DOI: 10.4236/IJCM.2021.122008
Wei Chen, Junwen Ye, Xiao-ping Tan, Yan Zhang, Jing-lin Liang, Mei-jin Huang
Objective: The purpose of this study was to observe the factors related to T4 patients who underwent surgery for colorectal cancer (CRC) with peritoneal carcinomatosis. Methods: 154 T4 colorectal cancer patients who underwent surgery in the first Affiliated Hospital of Sun Yat-sen University were included in the study between August, 1994 and December, 2005. Some clinical variables were selected and statistically correlated with prognosis. Results: The overall survival time was 91.7 months at the end of December of 2010 or death. The complete cytoreduction had significant survival benefit than the palliative surgery group. The age, location, histological grade, complete cytoreduction and liver metastasis were associated with overall survival time (OS) according to the univariate analysis (P < 0.05). In addition, Cox multivariate analysis showed that the complete cytoreduction (CCR) and liver metastasis were independent factor influencing survival. Conclusion: Compared with palliative surgery, the incomplete cytoreduction fails to improve patient prognosis. Patients performed completed cytoreduction have a relative good prognosis.
目的:本研究的目的是观察T4患者行结直肠癌合并腹膜癌手术的相关因素。方法:选取1994年8月至2005年12月中山大学附属第一医院行手术治疗的154例T4结直肠癌患者为研究对象。选择一些临床变量与预后有统计学相关性。结果:2010年12月底总生存时间为91.7个月或死亡。与姑息性手术组相比,完全细胞减少组有显著的生存优势。单因素分析显示,年龄、部位、组织学分级、完全细胞减少和肝转移与总生存时间(OS)相关(P < 0.05)。此外,Cox多因素分析显示,完全细胞减少(complete cytoreduction, CCR)和肝转移是影响生存的独立因素。结论:与姑息性手术相比,不完全细胞减少术不能改善患者预后。完成细胞减少术的患者预后相对较好。
{"title":"Analysis of 154 T4 Colorectal Cancer Patients with Peritoneal Carcinomatosis Treated by Surgery","authors":"Wei Chen, Junwen Ye, Xiao-ping Tan, Yan Zhang, Jing-lin Liang, Mei-jin Huang","doi":"10.4236/IJCM.2021.122008","DOIUrl":"https://doi.org/10.4236/IJCM.2021.122008","url":null,"abstract":"Objective: The purpose of this study was to observe the factors related to T4 patients who underwent surgery for colorectal cancer (CRC) with peritoneal carcinomatosis. Methods: 154 T4 colorectal cancer patients who underwent surgery in the first Affiliated Hospital of Sun Yat-sen University were included in the study between August, 1994 and December, 2005. Some clinical variables were selected and statistically correlated with prognosis. Results: The overall survival time was 91.7 months at the end of December of 2010 or death. The complete cytoreduction had significant survival benefit than the palliative surgery group. The age, location, histological grade, complete cytoreduction and liver metastasis were associated with overall survival time (OS) according to the univariate analysis (P < 0.05). In addition, Cox multivariate analysis showed that the complete cytoreduction (CCR) and liver metastasis were independent factor influencing survival. Conclusion: Compared with palliative surgery, the incomplete cytoreduction fails to improve patient prognosis. Patients performed completed cytoreduction have a relative good prognosis.","PeriodicalId":14201,"journal":{"name":"International Journal of Physical Medicine and Rehabilitation","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73449968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Efficacy Analysis of Glucocorticoids in the Treatment of Allergic Purpura in Tibetan Children 糖皮质激素治疗藏族儿童过敏性紫癜的疗效分析
Pub Date : 2021-01-08 DOI: 10.4236/IJCM.2021.121003
Xiangyun Zhang, Zha-Ba Nima, Shu-ning Zhang, Wangdui Suona, Ciren Pubu, Shengyou Yu
Background: Henoch Schonlein Purpura (HSP) is a common immune-related allergic disease in children. It is very important to understand the clinical features of this disease for doctors. Objective: To explore the clinical efficacy of glucocorticoids in the treatment of HSP in Tibetan children at high altitude, and to analyze the possible causes of HSP in children at high altitude. The risk factors of the disease provide a reference for the treatment of HSP in children in high altitude areas. Methods: Selecting January 2015 to November 2020, 88 children diagnosed with Henoch-Schonlein Purpura in the outpatient and inpatient departments of the People’s Hospital of Bomi County, Tibet Autonomous Region were the subjects of the study. Its gender, age of onset, season of onset, predisposing factors, allergy history, first symptoms, clinical manifestations, laboratory examinations, etc., perform retrospective analysis. Results: Among 88 children with allergic purpura, 55 were boys, accounting for 62.5%, and 33 were girls, accounting for 37.5%. Men have more cases than women. All have clinical manifestations of purpura of the skin, among which 35 cases have obvious triggers, of which the above there were 26 cases of respiratory infections, 6 cases of dietary factors, and 3 cases of contact with allergic substances. Simple skin type: 18 cases, accounting for 20.45%; Abdominal type: 6 cases, accounting for 6.82%; 2 male cases, accounting for 33.33%; 4 female cases, accounting for 66.67%; Articular type: 8 cases, accounting for 33.33%; Renal type: 2 cases, accounting for 2.27%; 54 cases of mixed type, accounting for 61.36%. After glucocorticoids, the rashes disappeared, no any adverse reactions. Conclusion: Allergic purpura in children is more common in school-age children, and upper respiratory tract infection is the main predisposing factor. Skin purpura is the main clinical manifestation, often associated with lower extremity joint swelling and pain. There is no significant difference in the efficacy and course of the disease between intravenous and oral treatment. Therefore, clinicians should strictly grasp the indications of glucocorticoids to reduce the occurrence of complications.
背景:过敏性紫癜(HSP)是儿童常见的免疫相关过敏性疾病。了解本病的临床特点对医生来说非常重要。目的:探讨糖皮质激素治疗高原藏族儿童热休克的临床疗效,并分析高原藏族儿童热休克的可能原因。该疾病的危险因素为高海拔地区儿童热休克的治疗提供参考。方法:选取2015年1月至2020年11月在西藏自治区波密县人民医院门诊部和住房部诊断为过敏性紫癜的88例患儿为研究对象。对其性别、发病年龄、发病季节、易感因素、过敏史、首发症状、临床表现、实验室检查等进行回顾性分析。结果:88例过敏性紫癜患儿中,男孩55例,占62.5%;女孩33例,占37.5%。男性的病例比女性多。均有皮肤紫癜的临床表现,其中有明显诱因35例,其中呼吸道感染26例,饮食因素6例,接触过敏物质3例。单纯性皮肤型:18例,占20.45%;腹部型:6例,占6.82%;男性2例,占33.33%;女性4例,占66.67%;关节型:8例,占33.33%;肾型:2例,占2.27%;混合型54例,占61.36%。经糖皮质激素治疗后,皮疹消失,无不良反应。结论:儿童过敏性紫癜多见于学龄儿童,上呼吸道感染是主要易感因素。皮肤紫癜是主要的临床表现,常伴有下肢关节肿胀和疼痛。静脉与口服治疗在疗效和病程上无显著差异。因此,临床医生应严格掌握糖皮质激素的适应症,以减少并发症的发生。
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引用次数: 2
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International Journal of Physical Medicine and Rehabilitation
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