Comparison of Cardiovascular Risk Factors Between Subjects With and Without Diabetes Mellitus: An Analytical Study

A. Mousavi, S. Asefzadeh, A. Ziaee, N. Esmailzadehha, A. Ghorbani
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Abstract

Background: Cardiovascular Disease (CVD) is developing treacherously along industrialization and development of urbanization Objectives: The aim of this study was to compare cardiovascular risk factors between subjects with and without diabetes mellitus in the Minoodar district of Qazvin. Patients and Methods: This analytical study was conducted on 100 subjects with diabetes and 140 subjects without diabetes in Qazvin from September 2010 to April 2011. Standardized measurements were available for waist circumference (WC), blood pressure (BP), fasting serum cholesterol, high-density lipoprotein cholesterol (HDL), and triglycerides (TGs). Cardiovascular risk factors were defined according to the diagnostic criteria proposed by the national cholesterol education program. Data were analyzed using the t-test, Mann-Whitney U test, and Chi-square test. Results: Overall, 12% of subjects with diabetes and 17.9% of subjects without diabetes were smokers (P = 0.277). The WC, TGs, systolic and diastolic BP were significantly higher in subjects with diabetes compared to subjects without diabetes. The prevalence of high WC, high BP, low HDL, and high TGs were significantly higher in subjects with diabetes compared to subjects without diabetes. Conclusions: Cardiovascular risk factors were higher in subjects with diabetes compared to subjects without diabetes. Lifestyle intervention programs should be focused on community education about reduction of CVD risk factors in patients with diabetes. Keywords: Risk Factor, Coronary Heart Disease, Diabetes Mellitus
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糖尿病患者与非糖尿病患者心血管危险因素比较:一项分析性研究
背景:随着工业化和城市化的发展,心血管疾病(CVD)正在迅速发展。目的:本研究的目的是比较加兹温Minoodar地区糖尿病患者和非糖尿病患者的心血管危险因素。患者与方法:本分析研究于2010年9月至2011年4月在加兹温市对100名糖尿病患者和140名非糖尿病患者进行研究。腰围(WC)、血压(BP)、空腹血清胆固醇、高密度脂蛋白胆固醇(HDL)和甘油三酯(tg)均可进行标准化测量。根据国家胆固醇教育计划提出的诊断标准确定心血管危险因素。数据分析采用t检验、Mann-Whitney U检验和卡方检验。结果:总体而言,12%的糖尿病患者和17.9%的非糖尿病患者是吸烟者(P = 0.277)。糖尿病患者的WC、tg、收缩压和舒张压明显高于非糖尿病患者。糖尿病患者的高WC、高BP、低HDL和高tg患病率明显高于非糖尿病患者。结论:糖尿病患者的心血管危险因素高于非糖尿病患者。生活方式干预项目应侧重于减少糖尿病患者心血管疾病危险因素的社区教育。关键词:危险因素,冠心病,糖尿病
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