Anti-diabetic, haematinic and anti-cholesterolmic effects of carrot (Daucus carota Linn.) juice metabolites to cure alloxan monohydrate induced type-1 diabetes in albino rats

K. Shachi, N. Dubey, Sanjeev Kumar, N. K. Prasad, U. Dubey
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引用次数: 3

Abstract

Introduction In present study an effort has been made to assess the hypoglycemic Anticholestrolemic and haematinic activity of carrot juice in alloxan monohydrate induced experimental animal model nbsp Materials and methods Rats were acclimatized for days in lab temperature All animals were given standard water and pellet diet Diabetes was induced in rats with the help of alloxan monohydrate mg kg body weight After alloxan monohydrate injection rats were separated and treatment started with carrot juice and insulin nbsp Results and discussion A marked rise in fasting blood glucose as well as serum cholesterol level was observed in diabetic control rats when compared to normal control rats Antihyperglycemic Anti cholesterolmic and haematinic activity observed in carrot juice administered rats on th th st and th days post treatment Anti hyperglycemic and anti cholesterol mic activity was found less effective than that of insulin treatment group nbsp Conclusion It is hope that present investigation will be helpful in establishing a scientific basis for antidiabetic haematinic and Anti cholesterolmic effects in experimental animal model The results are lt statistically significant
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胡萝卜(Daucus carota Linn.)果汁代谢物治疗白化大鼠四氧嘧啶诱导的1型糖尿病的降糖、降血和降胆固醇作用
本研究对胡萝卜汁在四氧嘧啶诱导实验动物模型中的降糖、降胆固醇、降血活性进行了研究。材料和方法将大鼠在实验室温度下驯化数天,所有动物均给予标准水和颗粒饲料,以mg kg体重的四氧嘧啶诱导大鼠发生糖尿病胡萝卜汁和胰岛素盼结果与讨论的显著上升空腹血糖以及血清胆固醇水平在糖尿病控制老鼠相比正常控制老鼠的降糖药反cholesterolmic和haematinic活动中观察到胡萝卜汁服用老鼠th st和th天治疗后抗高血糖的发现和抗胆固醇麦克风活动效果低于胰岛素治疗组的结论是盼希望礼物本研究将有助于在实验动物模型上建立抗糖尿病、降血脂和降胆固醇作用的科学依据
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