A Case series of ABPA with rare radiological presentation

Sudhir Kumar, D. Rai, Subhash Kumar
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引用次数: 1

Abstract

Allergic bronchopulmonary aspergillosis (ABPA) is an immunologically mediated lung disease that occurs in response to Aspergillus fumigatus which affects primarily asthmatic and cystic fibrosis patients. Central bronchiectasis is a classical radiological presentation of ABPA, but the presentation as total collapse of the lung, pneumothorax, lung mass, or fibrocavitary disease has been rarely described. First case was a 50-year-old nonsmoker male who presented radiologically as complete collapse of left lung. The second case was 54-year-old nonsmoker male presented with breathlessness and chest radiograph showed right-sided pneumothorax which expand after chest tube insertion. The third case a 35-year-old female who treated as bronchial asthma and refer to us for provisional diagnosis of malignancy after saw chest radiograph. The last case was a 22-year-old male who had typical symptoms and radiologically features of pulmonary tuberculosis. All these patients were treated by antitubercular drug, but later, all four case turn out as ABPA. This case series highlights the rare radiological presentation of ABPA (pneumothorax, lung collapse, lung mass, and fibrocavitary), and identifying these diseases in the early stage can prevent the development of end-stage pulmonary fibrosis.
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ABPA病例系列,影像学表现罕见
过敏性支气管肺曲霉病(ABPA)是一种免疫介导的肺部疾病,主要影响哮喘和囊性纤维化患者,是对烟曲霉的反应。中枢性支气管扩张是ABPA的典型影像学表现,但表现为肺完全塌陷、气胸、肺肿块或纤维腔疾病的病例很少报道。第一个病例是一位50岁的不吸烟男性,放射学表现为左肺完全塌陷。第二例患者为54岁男性,不吸烟,呼吸困难,胸片示右侧气胸,胸管插入后扩大。第三例为35岁女性,诊断为支气管哮喘,胸片检查后暂定诊断为恶性肿瘤。最后一个病例是22岁的男性,他有典型的肺结核症状和放射学特征。4例患者均经抗结核药物治疗,但均为ABPA。本病例系列强调ABPA罕见的影像学表现(气胸、肺塌陷、肺肿块和纤维空洞),早期识别这些疾病可以预防终末期肺纤维化的发展。
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