The Efficacy of Steamed Ginger Extract versus Placebo for Pain Relief at the Perineum and Uterus in First Normal Postpartum Women

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Abstract

Background: Perineal and uterine pain are common postpartum complaint. Objective: To compare the efficacy of steamed ginger extract, paracetamol, a stand analgesic used in Western medicine, and placebo for pain relief at the perineum and uterus in first normal postpartum women. Materials and Methods: First pregnancy, postpartum women, who had a normal vaginal delivery, were given 3-day 200 mg tid of ginger extract/placebo capsules, or up to 500 mg qid paracetamol in an open randomized (1:1:1) trial. All drugs were given within two hours of delivery. The Numerical Rating Scale was used for pain assessment at 2, 24, 48, 72 hours postpartum. Ninety-nine women were recruited with similar demographic characteristics at the postnatal ward of Thammasat University Hospital. Results: All groups showed decreasing mean perineal and uterine pain scores over time. The only significant differences in mean scores were seen for perineal pain at 24, 48, and 72 hours in the ginger extract versus the placebo arms at 3.97 versus 6.3, 2.48 versus 6.09, and 1.42 versus 2.61, respectively. There were no adverse drug reactions reported in any of the three arms. Conclusion: Ginger extract capsules showed promising results and having no adverse reactions, so this should be developed further. Keywords; Steamed Ginger Extract; Perineum Pain; Postpartum Women
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蒸姜提取物与安慰剂对首次正常产后妇女会阴和子宫疼痛缓解的疗效比较
背景:会阴和子宫疼痛是常见的产后主诉。目的:比较蒸姜提取物、西药常用镇痛药扑热息痛和安慰剂对初次正常产后妇女会阴、子宫疼痛的缓解效果。材料和方法:在一项开放随机(1:1:1)试验中,首次怀孕、产后正常阴道分娩的妇女给予3天200毫克生姜提取物/安慰剂胶囊,或500毫克每日扑热息痛。所有药物都是在分娩后两小时内服用的。分别于产后2、24、48、72小时采用数值评定量表进行疼痛评估。在法政大学医院的产后病房招募了99名具有相似人口特征的妇女。结果:所有组的会阴和子宫疼痛评分均随时间降低。生姜提取物组与安慰剂组在24、48和72小时的会阴疼痛平均评分上的唯一显著差异分别为3.97比6.3,2.48比6.09,1.42比2.61。三个组中均未报告药物不良反应。结论:生姜提取物胶囊疗效良好,无不良反应,值得进一步开发。清蒸姜精;会阴部疼痛;产后妇女
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